Source: RGD

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.600 None 1.000 1 0 1999 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.510 None 1.000 1 0 2002 2008
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.510 None 1.000 1 0 2002 2015
Entrez Id: 1634
Gene Symbol: DCN
DCN
decorin 0.457 0.808 0.31
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.500 None 1.000 1 0 2005 2005
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.500 None 1.000 1 0 2003 2011
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
cellular communication network factor 2 0.399 0.846 5.0E-04
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.260 None 1.000 1 0 2003 2008
Entrez Id: 3596
Gene Symbol: IL13
IL13
interleukin 13 0.386 0.846 1.4E-02
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.240 None 1.000 1 0 2003 2008
Entrez Id: 387
Gene Symbol: RHOA
RHOA
ras homolog family member A 0.502 0.808 0.60
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.210 None 1.000 1 0 2005 2006
Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1
bradykinin receptor B1 0.619 0.731 4.7E-03
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.210 None 1.000 1 0 2004 2009
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.210 None 1.000 1 0 2008 2012
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
angiotensin II receptor type 1 0.423 0.846 5.3E-04
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.210 None 1.000 1 0 1997 2011
Entrez Id: 177
Gene Symbol: AGER
AGER
advanced glycosylation end-product specific receptor 0.420 0.885 6.4E-16
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.210 None 1.000 1 0 2003 2008
Entrez Id: 4060
Gene Symbol: LUM
LUM
lumican 0.543 0.731 7.7E-02
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 2 0 1992 2003
Entrez Id: 8841
Gene Symbol: HDAC3
HDAC3
histone deacetylase 3 0.511 0.731 0.57
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2014 2014
Entrez Id: 811
Gene Symbol: CALR
CALR
calreticulin 0.413 0.923 0.89
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2008 2008
Entrez Id: 80781
Gene Symbol: COL18A1
COL18A1
collagen type XVIII alpha 1 chain 0.449 0.808 1.7E-10
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2001 2001
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
suppressor of cytokine signaling 3 0.434 0.808 0.75
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
cyclin dependent kinase inhibitor 1B 0.409 0.769 0.62
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2004 2004
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
C-C motif chemokine ligand 11 0.473 0.885 1.0E-02
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2008 2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
angiotensin II receptor type 2 0.496 0.808 8.2E-03
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2012 2012
Entrez Id: 1584
Gene Symbol: CYP11B1
CYP11B1
cytochrome P450 family 11 subfamily B member 1 0.563 0.615 8.2E-07
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2006 2006
Entrez Id: 9759
Gene Symbol: HDAC4
HDAC4
histone deacetylase 4 0.484 0.885 1.00
CUI: C0016059
Disease: Fibrosis
Fibrosis
phenotype 0.200 None 1.000 1 0 2014 2014