| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
protein tyrosine phosphatase non-receptor type 11 | 0.385 | 0.923 | 1.00 |
|
disease | 1.000 | definitive | 0.987 | 7 | 0 | 2001 | 2020 | ||||||||
|
SOS Ras/Rac guanine nucleotide exchange factor 1 | 0.485 | 0.808 | 1.00 |
|
disease | 1.000 | definitive | 0.969 | 4 | 0 | 1991 | 2019 | ||||||||
|
Raf-1 proto-oncogene, serine/threonine kinase | 0.418 | 0.885 | 0.85 |
|
disease | 1.000 | definitive | 1.000 | 2 | 0 | 1992 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 1.000 | definitive | 0.985 | 2 | 0 | 1993 | 2019 | ||||||||
|
leucine zipper like transcription regulator 1 | 0.547 | 0.808 | 1.0E-92 |
|
disease | 0.900 | strong | 1.000 | 1 | 0 | 2014 | 2020 | ||||||||
|
SHOC2 leucine rich repeat scaffold protein | 0.593 | 0.769 | 1.00 |
|
disease | 0.800 | disputed | 0.957 | 1 | 0 | 2009 | 2019 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
disease | 0.780 | definitive | 1.000 | 4 | 0 | 2000 | 2019 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.770 | moderate | 1.000 | 2 | 0 | 2003 | 2019 | ||||||||
|
RAS related 2 | 0.656 | 0.500 | 0.97 |
|
disease | 0.620 | strong | 1.000 | 1 | 0 | 2014 | 2019 | ||||||||
|
SOS Ras/Rho guanine nucleotide exchange factor 2 | 0.608 | 0.692 | 1.00 |
|
disease | 0.620 | moderate | 1.000 | 1 | 0 | 2000 | 2015 | ||||||||
|
alpha-2-macroglobulin like 1 | 0.590 | 0.692 | 1.6E-34 |
|
disease | 0.600 | disputed | 1.000 | 2 | 0 | 2015 | 2016 | ||||||||
|
Cbl proto-oncogene | 0.527 | 0.769 | 6.1E-04 |
|
disease | 0.460 | strong | 1.000 | 1 | 0 | 2009 | 2016 | ||||||||
|
neurofibromin 1 | 0.440 | 0.885 | 0.90 |
|
disease | 0.350 | strong | 1.000 | 1 | 0 | 1993 | 2013 |