Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2200
Gene Symbol: FBN1
FBN1 		fibrillin 1 0.417 0.846 1.00
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 20 0 1980 2001
Entrez Id: 26258
Gene Symbol: BLOC1S6
BLOC1S6 		biogenesis of lysosomal organelles complex 1 subunit 6 0.769 0.308 8.0E-09
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 12 0 1971 2015
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 5 0 2006 2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA 		NFKB inhibitor alpha 0.487 0.885 0.99
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA 		endothelin receptor type A 0.426 0.885 0.99
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 80198
Gene Symbol: MUS81
MUS81 		MUS81 structure-specific endonuclease subunit 0.686 0.462 8.8E-13
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2014 2014
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 9365
Gene Symbol: KL
KL 		klotho 0.448 0.769 2.2E-04
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 1997 1997
Entrez Id: 3694
Gene Symbol: ITGB6
ITGB6 		integrin subunit beta 6 0.597 0.692 1.6E-22
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 3606
Gene Symbol: IL18
IL18 		interleukin 18 0.365 0.923 3.1E-02
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2013 2013
Entrez Id: 3066
Gene Symbol: HDAC2
HDAC2 		histone deacetylase 2 0.476 0.846 1.00
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2013 2013
Entrez Id: 2729
Gene Symbol: GCLC
GCLC 		glutamate-cysteine ligase catalytic subunit 0.509 0.885 0.43
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 2530
Gene Symbol: FUT8
FUT8 		fucosyltransferase 8 0.603 0.692 9.9E-03
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 2243
Gene Symbol: FGA
FGA 		fibrinogen alpha chain 0.573 0.769 1.2E-13
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 1991
Gene Symbol: ELANE
ELANE 		elastase, neutrophil expressed 0.447 0.846 1.2E-03
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 6608
Gene Symbol: SMO
SMO 		smoothened, frizzled class receptor 0.489 0.731 4.3E-07
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 0 0
Entrez Id: 3725
Gene Symbol: JUN
JUN 		Jun proto-oncogene, AP-1 transcription factor subunit 0.442 0.885 6.0E-02
CUI: C0029607
Disease: Other emphysema
Other emphysema 		phenotype 0.200 None 0 0