Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0032584
Disease: polyps
polyps
phenotype 0.100 None 1.000 5 0 1999 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0032584
Disease: polyps
polyps
phenotype 0.100 None 0.977 3 0 2003 2019
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0032584
Disease: polyps
polyps
phenotype 0.100 None 0.878 3 0 1992 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0032584
Disease: polyps
polyps
phenotype 0.100 None 1.000 3 0 1995 2020
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.399 0.808 3.4E-05
CUI: C0032584
Disease: polyps
polyps
phenotype 0.100 None 0.955 2 0 2003 2019
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
mutY DNA glycosylase 0.521 0.769 1.3E-18
CUI: C0032584
Disease: polyps
polyps
phenotype 0.100 None 0.867 1 0 2004 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0032584
Disease: polyps
polyps
phenotype 0.100 None 1.000 1 0 2001 2020
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
mucin 5AC, oligomeric mucus/gel-forming 0.483 0.808 1.0E-08
CUI: C0032584
Disease: polyps
polyps
phenotype 0.090 None 0.889 1 0 1999 2016
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
mucin 2, oligomeric mucus/gel-forming 0.486 0.808 9.4E-10
CUI: C0032584
Disease: polyps
polyps
phenotype 0.080 None 0.875 1 0 2000 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0032584
Disease: polyps
polyps
phenotype 0.040 None 1.000 1 0 2007 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0032584
Disease: polyps
polyps
phenotype 0.040 None 0.750 1 0 2006 2012
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
marker of proliferation Ki-67 0.431 0.808 1.3E-28
CUI: C0032584
Disease: polyps
polyps
phenotype 0.030 None 1.000 1 0 2000 2006
Entrez Id: 947
Gene Symbol: CD34
CD34
CD34 molecule 0.368 0.808 5.0E-06
CUI: C0032584
Disease: polyps
polyps
phenotype 0.020 None 1.000 1 0 2008 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0032584
Disease: polyps
polyps
phenotype 0.020 None 1.000 1 0 2007 2008
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
cytochrome P450 family 19 subfamily A member 1 0.410 0.885 1.7E-05
CUI: C0032584
Disease: polyps
polyps
phenotype 0.020 None 1.000 1 0 2006 2011
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
RUNX family transcription factor 3 0.459 0.731 0.84
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2009 2009
Entrez Id: 794
Gene Symbol: CALB2
CALB2
calbindin 2 0.545 0.692 4.5E-07
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2008 2008
Entrez Id: 7033
Gene Symbol: TFF3
TFF3
trefoil factor 3 0.518 0.885 1.6E-02
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2005 2005
Entrez Id: 7031
Gene Symbol: TFF1
TFF1
trefoil factor 1 0.529 0.769 8.9E-04
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2005 2005
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
cyclin dependent kinase inhibitor 2B 0.417 0.769 7.3E-03
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2004 2004
Entrez Id: 634
Gene Symbol: CEACAM1
CEACAM1
CEA cell adhesion molecule 1 0.525 0.731 7.9E-04
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2004 2004
Entrez Id: 5651
Gene Symbol: TMPRSS15
TMPRSS15
transmembrane serine protease 15 0.751 0.385 4.6E-32
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2003 2003
Entrez Id: 54822
Gene Symbol: TRPM7
TRPM7
transient receptor potential cation channel subfamily M member 7 0.531 0.731 5.2E-16
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2007 2007
Entrez Id: 5047
Gene Symbol: PAEP
PAEP
progestagen associated endometrial protein 0.430 0.846 3.1E-08
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2002 2002
Entrez Id: 3630
Gene Symbol: INS
INS
insulin 0.445 0.923 0.30
CUI: C0032584
Disease: polyps
polyps
phenotype 0.010 None 1.000 1 0 2008 2008