| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
dyskerin pseudouridine synthase 1 | 0.547 | 0.769 | 1.00 |
|
disease | 0.900 | strong | 0.969 | 4 | 0 | 1998 | 2019 | ||||||||
|
TERF1 interacting nuclear factor 2 | 0.575 | 0.731 | 1.3E-03 |
|
disease | 0.900 | None | 0.917 | 4 | 0 | 2008 | 2018 | ||||||||
|
telomerase RNA component | 0.471 | 0.846 |
|
disease | 0.700 | None | 1.000 | 4 | 0 | 2001 | 2019 | |||||||||
|
regulator of telomere elongation helicase 1 | 0.459 | 0.808 | 8.9E-10 |
|
disease | 0.690 | strong | 1.000 | 1 | 0 | 2013 | 2018 | ||||||||
|
poly(A)-specific ribonuclease | 0.575 | 0.769 | 3.7E-04 |
|
disease | 0.670 | strong | 1.000 | 1 | 0 | 2015 | 2019 | ||||||||
|
WD repeat containing antisense to TP53 | 0.603 | 0.692 | 5.4E-05 |
|
disease | 0.650 | moderate | 1.000 | 3 | 0 | 2010 | 2019 | ||||||||
|
CST telomere replication complex component 1 | 0.601 | 0.538 | 1.6E-11 |
|
disease | 0.640 | None | 1.000 | 4 | 0 | 2012 | 2019 | ||||||||
|
telomerase reverse transcriptase | 0.374 | 0.846 | 0.99 |
|
disease | 0.600 | None | 1.000 | 3 | 0 | 2005 | 2019 | ||||||||
|
U6 snRNA biogenesis phosphodiesterase 1 | 0.636 | 0.577 | 6.9E-04 |
|
disease | 0.550 | None | 1.000 | 1 | 0 | 2010 | 2016 | ||||||||
|
nucleophosmin 1 | 0.464 | 0.846 | 1.00 |
|
disease | 0.510 | moderate | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
NOP10 ribonucleoprotein | 0.631 | 0.654 | 0.77 |
|
disease | 0.470 | None | 1.000 | 3 | 0 | 2006 | 2018 | ||||||||
|
NHP2 ribonucleoprotein | 0.623 | 0.654 | 5.0E-02 |
|
disease | 0.430 | None | 1.000 | 4 | 0 | 2001 | 2019 | ||||||||
|
nuclear assembly factor 1 ribonucleoprotein | 0.700 | 0.500 | 0.98 |
|
disease | 0.320 | strong | 1.000 | 1 | 0 | 2010 | 2019 | ||||||||
|
ACD shelterin complex subunit and telomerase recruitment factor | 0.603 | 0.731 | 1.1E-12 |
|
disease | 0.310 | strong | 1.000 | 1 | 0 | 2016 | 2017 | ||||||||
|
STN1 subunit of CST complex | 0.604 | 0.769 | 2.3E-10 |
|
disease | 0.300 | strong | 1.000 | 1 | 0 | 2017 | 2017 |