Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
cytotoxic T-lymphocyte associated protein 4 0.369 0.923 0.94
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.500 None 0.955 5 0 1998 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.100 None 1.000 2 0 2001 2019
Entrez Id: 7173
Gene Symbol: TPO
TPO
thyroid peroxidase 0.455 0.846 1.8E-21
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.100 None 0.978 1 0 1989 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 0.333 0.923 1.1E-03
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.100 None 1.000 1 0 1996 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.100 None 1.000 1 0 2000 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.100 None 1.000 1 0 1992 2015
Entrez Id: 7421
Gene Symbol: VDR
VDR
vitamin D receptor 0.352 0.885 1.7E-05
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.090 None 1.000 1 0 2006 2019
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
C-X-C motif chemokine ligand 10 0.378 0.885 0.37
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.090 None 0.889 1 0 2003 2019
Entrez Id: 355
Gene Symbol: FAS
FAS
Fas cell surface death receptor 0.372 0.923 0.81
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.070 None 1.000 2 0 2000 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.060 None 1.000 1 0 2008 2018
Entrez Id: 356
Gene Symbol: FASLG
FASLG
Fas ligand 0.430 0.885 0.18
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.040 None 1.000 2 0 2000 2017
Entrez Id: 3565
Gene Symbol: IL4
IL4
interleukin 4 0.332 0.962 4.7E-03
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.040 None 1.000 1 0 2008 2018
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1 0.407 0.885 8.9E-03
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.030 None 1.000 1 0 1993 2008
Entrez Id: 1594
Gene Symbol: CYP27B1
CYP27B1
cytochrome P450 family 27 subfamily B member 1 0.502 0.769 1.9E-07
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.020 None 1.000 2 0 2002 2004
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.380 0.846 0.46
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.020 None 1.000 1 0 2003 2014
Entrez Id: 3126
Gene Symbol: HLA-DRB4
HLA-DRB4
major histocompatibility complex, class II, DR beta 4 0.565 0.846
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.020 None 1.000 1 0 2003 2014
Entrez Id: 841
Gene Symbol: CASP8
CASP8
caspase 8 0.404 0.923 3.7E-06
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.020 None 1.000 1 0 2003 2008
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8
TNF receptor superfamily member 8 0.444 0.808 0.86
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.010 None 1.000 1 0 2006 2006
Entrez Id: 911
Gene Symbol: CD1C
CD1C
CD1c molecule 0.633 0.692 1.6E-08
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.010 None 1.000 1 0 2005 2005
Entrez Id: 909
Gene Symbol: CD1A
CD1A
CD1a molecule 0.543 0.769 4.2E-24
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.010 None 1.000 1 0 2005 2005
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
interleukin 6 receptor 0.471 0.846 3.2E-05
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.010 None 1.000 1 0 2006 2006
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
C-C motif chemokine ligand 5 0.403 0.885 1.8E-03
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.010 None 1.000 1 0 2008 2008
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.010 None 1.000 1 0 2007 2007
Entrez Id: 944
Gene Symbol: TNFSF8
TNFSF8
TNF superfamily member 8 0.610 0.538 0.76
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease
disease 0.010 None 1.000 1 0 2006 2006