| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.200 | None | 0.980 | 195 | 5 | 1983 | 2019 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.400 | None | 0.916 | 183 | 7 | 1992 | 2020 | ||||||||
|
lipoprotein(a) | 0.444 | 0.769 | 6.6E-89 |
|
disease | 0.500 | None | 0.958 | 159 | 10 | 1988 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.400 | None | 0.947 | 141 | 4 | 1999 | 2020 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.500 | None | 0.918 | 116 | 14 | 1996 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 0.936 | 108 | 4 | 2001 | 2020 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.200 | None | 0.900 | 107 | 6 | 1991 | 2020 | ||||||||
|
paraoxonase 1 | 0.409 | 0.885 | 9.8E-11 |
|
disease | 0.400 | None | 0.917 | 104 | 2 | 1995 | 2019 | ||||||||
|
apolipoprotein B | 0.453 | 0.808 | 1.9E-16 |
|
disease | 0.100 | None | 0.950 | 98 | 8 | 1986 | 2019 | ||||||||
|
cholesteryl ester transfer protein | 0.512 | 0.731 | 1.2E-23 |
|
disease | 0.100 | None | 0.935 | 91 | 9 | 1990 | 2019 | ||||||||
|
adiponectin, C1Q and collagen domain containing | 0.376 | 0.885 | 4.6E-09 |
|
disease | 0.100 | None | 0.980 | 87 | 7 | 2000 | 2019 | ||||||||
|
low density lipoprotein receptor | 0.449 | 0.885 | 9.8E-24 |
|
disease | 0.500 | None | 0.989 | 85 | 15 | 1986 | 2020 | ||||||||
|
lipoprotein lipase | 0.474 | 0.808 | 1.3E-09 |
|
disease | 0.200 | None | 0.918 | 81 | 8 | 1993 | 2020 | ||||||||
|
proprotein convertase subtilisin/kexin type 9 | 0.482 | 0.808 | 2.7E-17 |
|
disease | 0.500 | None | 0.987 | 71 | 3 | 2006 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.917 | 69 | 4 | 2001 | 2020 | ||||||||
|
apolipoprotein A1 | 0.429 | 0.885 | 5.5E-04 |
|
disease | 0.400 | None | 0.938 | 60 | 4 | 1986 | 2019 | ||||||||
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
disease | 0.200 | None | 0.933 | 59 | 6 | 1995 | 2019 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
disease | 0.100 | None | 0.966 | 58 | 1 | 1996 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.400 | None | 0.931 | 57 | 6 | 1999 | 2019 | ||||||||
|
ATP binding cassette subfamily A member 1 | 0.467 | 0.846 | 1.5E-13 |
|
disease | 0.200 | None | 0.982 | 54 | 11 | 2000 | 2019 | ||||||||
|
serpin family E member 1 | 0.359 | 0.885 | 4.4E-02 |
|
disease | 0.100 | None | 0.926 | 52 | 3 | 1992 | 2019 | ||||||||
|
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.482 | 0.846 | 1.00 |
|
disease | 0.100 | None | 0.980 | 51 | 3 | 1992 | 2019 | ||||||||
|
apolipoprotein A5 | 0.587 | 0.615 | 5.6E-10 |
|
disease | 0.500 | None | 0.938 | 46 | 5 | 2001 | 2019 | ||||||||
|
cytochrome P450 family 2 subfamily C member 19 | 0.467 | 0.846 | 6.5E-20 |
|
disease | 0.100 | None | 0.977 | 44 | 1 | 2009 | 2019 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.100 | None | 1.000 | 42 | 4 | 2002 | 2020 |