| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
group | 0.600 | None | 0.971 | 797 | 21 | 1979 | 2020 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
group | 0.600 | None | 0.969 | 675 | 3 | 1975 | 2020 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
group | 0.600 | None | 0.921 | 546 | 15 | 1986 | 2020 | ||||||||
|
angiotensin II receptor type 1 | 0.423 | 0.846 | 5.3E-04 |
|
group | 0.600 | None | 0.944 | 198 | 7 | 1993 | 2020 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
group | 0.700 | None | 0.942 | 156 | 11 | 1996 | 2019 | ||||||||
|
sex hormone binding globulin | 0.438 | 0.808 | 1.3E-06 |
|
group | 0.100 | None | 0.942 | 121 | 3 | 1999 | 2020 | ||||||||
|
endothelin 1 | 0.380 | 0.846 | 0.46 |
|
group | 0.600 | None | 0.983 | 116 | 1 | 1993 | 2020 | ||||||||
|
coiled-coil alpha-helical rod protein 1 | 0.505 | 0.808 | 1.0E-16 |
|
group | 0.100 | None | 0.939 | 114 | 3 | 1999 | 2020 | ||||||||
|
selenium binding protein 1 | 0.493 | 0.846 | 3.2E-16 |
|
group | 0.100 | None | 0.939 | 114 | 4 | 1999 | 2020 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
group | 0.600 | None | 0.944 | 107 | 0 | 2003 | 2020 | ||||||||
|
cytochrome P450 family 11 subfamily B member 2 | 0.553 | 0.615 | 7.1E-19 |
|
group | 0.200 | None | 0.969 | 98 | 9 | 1992 | 2019 | ||||||||
|
proopiomelanocortin | 0.356 | 0.846 | 1.2E-04 |
|
group | 0.400 | None | 0.989 | 91 | 0 | 1974 | 2020 | ||||||||
|
angiopoietin 2 | 0.410 | 0.846 | 0.83 |
|
group | 0.100 | None | 0.989 | 88 | 0 | 1999 | 2020 | ||||||||
|
VPS51 subunit of GARP complex | 0.452 | 0.846 | 1.1E-08 |
|
group | 0.100 | None | 0.988 | 86 | 0 | 1999 | 2020 | ||||||||
|
nuclear receptor subfamily 3 group C member 2 | 0.469 | 0.846 | 0.84 |
|
group | 0.200 | None | 1.000 | 81 | 7 | 1995 | 2020 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
group | 0.700 | None | 0.897 | 78 | 1 | 1994 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
group | 0.100 | None | 1.000 | 77 | 5 | 1997 | 2020 | ||||||||
|
albumin | 0.317 | 0.962 | 0.64 |
|
group | 0.400 | None | 0.947 | 75 | 1 | 1989 | 2020 | ||||||||
|
adducin 1 | 0.612 | 0.615 | 0.99 |
|
group | 0.600 | None | 0.861 | 72 | 5 | 1995 | 2019 | ||||||||
|
D-box binding PAR bZIP transcription factor | 0.556 | 0.731 | 0.23 |
|
group | 0.100 | None | 0.944 | 72 | 0 | 1988 | 2020 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
group | 0.600 | None | 0.972 | 71 | 2 | 1998 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
group | 0.400 | None | 0.970 | 66 | 3 | 1999 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
group | 0.600 | None | 1.000 | 66 | 0 | 1998 | 2020 | ||||||||
|
G protein subunit beta 3 | 0.518 | 0.808 | 3.3E-11 |
|
group | 0.400 | None | 0.938 | 65 | 2 | 1998 | 2018 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
group | 0.700 | None | 1.000 | 62 | 10 | 1999 | 2020 |