×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Asthma
0.240
Biomarker
RGD
ERB -041 [7-ethenyl-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol], an ERbeta agonist, was profiled on cytokine release from interleukin-1beta-stimulated human airway smooth muscle (HASM) cells and in the rodent asthma model.
18375789
2008
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Hyperalgesia
0.200
Biomarker
RGD
An estrogen receptor-beta agonist is active in models of inflammatory and chemical-induced pain.
17056036
2006
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Osteoporotic Fractures
0.220
Biomarker
RGD
Callus formation is related to the expression ratios of estrogen receptors-alpha and -beta in ovariectomy-induced osteoporotic fracture healing.
25085540
2014
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Anxiety Disorders
0.250
Therapeutic
RGD
Chaihu-Shugan-San administration ameliorates perimenopausal anxiety and depression in rats.
24015243
2013
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Malignant neoplasm of breast
0.600
Therapeutic
RGD
Diffusion weighted imaging evaluated the early therapy effect of tamoxifen in an MNU-induced mammary cancer rat model.
23700476
2013
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Urination Disorders
0.200
Therapeutic
RGD
Effects of agonists for estrogen receptor α and β on ovariectomy-induced lower urinary tract dysfunction in the rat.
24259512
2014
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Mental Depression
0.250
Therapeutic
RGD
Estradiol decreases rat depressive behavior by estrogen receptor beta but not alpha: no correlation with plasma corticosterone.
24128867
2014
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Brain Ischemia
0.210
Biomarker
RGD
Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors.
10414967
1999
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Other specified peritonitis
0.200
Therapeutic
RGD
Estradiol receptors agonists induced effects in rat intestinal microcirculation during sepsis.
23063870
2013
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Lung Injury
0.200
Biomarker
RGD
Estrogen receptor hormone agonists limit trauma hemorrhage shock-induced gut and lung injury in rats.
20195535
2010
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Anxiety Disorders
0.250
Therapeutic
RGD
Estrogen receptor β and oxytocin interact to modulate anxiety-like behavior and neuroendocrine stress reactivity in adult male and female rats.
24631553
2014
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Hypertensive disease
0.300
Biomarker
RGD
Estrogen receptor-β in the paraventricular nucleus and rostroventrolateral medulla plays an essential protective role in aldosterone/salt-induced hypertension in female rats.
23608653
2013
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Colitis
0.230
Biomarker
RGD
Estrogen receptor-β signaling modulates epithelial barrier function.
21252046
2011
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Pulmonary Hypertension
0.200
Biomarker
RGD
Estrogen rescues preexisting severe pulmonary hypertension in rats.
21700911
2011
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Inflammatory Bowel Diseases
0.250
Biomarker
RGD
However, ERB -041 has a dramatic beneficial effect in the HLA-B27 transgenic rat model of inflammatory bowel disease and the Lewis rat adjuvant-induced arthritis model.
14500559
2003
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Cerebrovascular accident
0.230
Therapeutic
RGD
Impact of estrogen receptor beta activation on functional recovery after experimental stroke .
24406718
2014
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Obesity
0.300
Biomarker
RGD
Impact of estradiol, ER subtype specific agonists and genistein on energy homeostasis in a rat model of nutrition induced obesity.
22230815
2012
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Hot flushes
0.220
Therapeutic
RGD
Novel ligands balance estrogen receptor β and α agonism for safe and effective suppression of the vasomotor response in the ovariectomized female rat model of menopause.
24823389
2014
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Carcinoma in situ of prostate
0.200
Therapeutic
RGD
Opposing roles of ERα and ERβ in the genesis and progression of adenocarcinoma in the rat ventral prostate.
22025007
2012
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Transient Ischemic Attack
0.200
Biomarker
RGD
Periodic 17β-estradiol pretreatment protects rat brain from cerebral ischemic damage via estrogen receptor-β.
23593292
2013
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Mammary Neoplasms, Experimental
0.500
Therapeutic
RGD
Simultaneous disruption of estrogen receptor and Wnt/β-catenin signaling is involved in methyl amooranin-mediated chemoprevention of mammary gland carcinogenesis in rats.
24078029
2013
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Malignant tumor of colon
0.300
Biomarker
RGD
Soy isoflavones modulate azoxymethane-induced rat colon carcinogenesis exposed pre- and postnatally and inhibit growth of DLD-1 human colon adenocarcinoma cells by increasing the expression of estrogen receptor-beta.
19141699
2009
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Mammary Neoplasms, Experimental
0.500
Biomarker
RGD
Steroid hormone receptor expression and proliferation in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
15637090
2005
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Cystitis
0.200
Biomarker
RGD
The effect of tamoxifen on bladder functions and histology, and the role of estrogen receptor beta in a rat chemical cystitis model.
16894621
2007
×
Entrez Id:
2100
Gene Symbol:
ESR2
ESR2
Sepsis
0.200
Biomarker
RGD
To determine the effect of an estrogen receptor-beta selective agent in experimental models of systemic infection and sepsis.
16755255
2006