Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Diabetes, a new mutation in the mouse. 5918576

1966

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Studies in the diabetic mutant mouse. VI. Evolution of glomerular lesions and associated proteinuria. 5009970

1972

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Studies of diabetic nephropathy in animals and man. 823065

1976

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Primary myocardial disease in the diabetic mouse. An ultrastructural study. 431046

1979

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD "Endocrine pancreatic cells of postnatal ""diabetes"" (db) mice in cell culture." 393618

1979

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Diabetic neuropathy in the mutant mouse [C57BL/ks(db/db)]: a morphometric study. 6991317

1980

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Anti-pancreatic immunity in genetically diabetic mice. 6339122

1983

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. 8177042

1994

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Brain-derived neurotrophic factor reduces blood glucose level in obese diabetic mice but not in normal mice. 9299565

1997

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Contrasting obesity phenotypes uncovered by partial leptin receptor gene deletion in transgenic mice. 10708583

2000

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Intraocular pressure in genetically distinct mice: an update and strain survey. 11532192

2001

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents. 12150780

2002

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. 12651605

2003

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Diabetes-induced, progressive endometrial involution characterization of periluminal epithelial lipoatrophy. 12502493

2003

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Conditioned taste aversion learning in leptin-receptor-deficient db/db mice. 12932425

2003

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice. 12540618

2003

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Night-time restricted feeding normalises clock genes and Pai-1 gene expression in the db/db mouse liver. 15309293

2004

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation. 15070774

2004

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD COX-2 up-regulation and vascular smooth muscle contractile hyperreactivity in spontaneous diabetic db/db mice. 15885672

2005

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice. 15685168

2005

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD The RAGE axis in early diabetic retinopathy. 16043866

2005

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice. 16971655

2006

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3beta. 16522636

2006

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Myocardial infarction and heart failure in the db/db diabetic mouse. 16113078

2006

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
Diabetes Mellitus, Non-Insulin-Dependent
0.600 Biomarker MGD Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice. 16443782

2006