|
| Entrez Id: |
5456 |
| Gene Symbol: |
POU3F4 |
POU3F4
|
Nonsyndromic Deafness
|
0.340 |
Biomarker |
CLINGEN |
Association between X-linked mixed deafness and mutations in the POU domain gene POU3F4.
|
7839145 |
1995 |
|
| Entrez Id: |
5456 |
| Gene Symbol: |
POU3F4 |
POU3F4
|
Nonsyndromic Deafness
|
0.340 |
Biomarker |
CLINGEN |
Further mutations in Brain 4 (POU3F4) clarify the phenotype in the X-linked deafness, DFN3.
|
7581392 |
1995 |
|
| Entrez Id: |
5459 |
| Gene Symbol: |
POU4F3 |
POU4F3
|
Nonsyndromic Deafness
|
0.360 |
Biomarker |
CLINGEN |
Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.
|
8637595 |
1996 |
|
| Entrez Id: |
4647 |
| Gene Symbol: |
MYO7A |
MYO7A
|
Nonsyndromic Deafness
|
0.400 |
Biomarker |
CLINGEN |
Autosomal dominant non-syndromic deafness caused by a mutation in the myosin VIIA gene.
|
9354784 |
1997 |
|
| Entrez Id: |
340990 |
| Gene Symbol: |
OTOG |
OTOG
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear.
|
9405633 |
1997 |
|
| Entrez Id: |
2707 |
| Gene Symbol: |
GJB3 |
GJB3
|
Nonsyndromic Deafness
|
0.500 |
Biomarker |
CLINGEN |
Mutations in the gene encoding gap junction protein beta-3 associated with autosomal dominant hearing impairment.
|
9843210 |
1998 |
|
| Entrez Id: |
51168 |
| Gene Symbol: |
MYO15A |
MYO15A
|
Nonsyndromic Deafness
|
0.480 |
Biomarker |
CLINGEN |
Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.
|
9603735 |
1998 |
|
| Entrez Id: |
5459 |
| Gene Symbol: |
POU4F3 |
POU4F3
|
Nonsyndromic Deafness
|
0.360 |
Biomarker |
CLINGEN |
Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans.
|
9506947 |
1998 |
|
| Entrez Id: |
1690 |
| Gene Symbol: |
COCH |
COCH
|
Nonsyndromic Deafness
|
0.340 |
Biomarker |
CLINGEN |
Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction.
|
9806553 |
1998 |
|
| Entrez Id: |
7007 |
| Gene Symbol: |
TECTA |
TECTA
|
Nonsyndromic Deafness
|
0.330 |
Biomarker |
CLINGEN |
Mutations in the human alpha-tectorin gene cause autosomal dominant non-syndromic hearing impairment.
|
9590290 |
1998 |
|
| Entrez Id: |
4254 |
| Gene Symbol: |
KITLG |
KITLG
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes.
|
9440696 |
1998 |
|
| Entrez Id: |
1302 |
| Gene Symbol: |
COL11A2 |
COL11A2
|
Nonsyndromic Deafness
|
0.400 |
Biomarker |
CLINGEN |
Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13).
|
10581026 |
1999 |
|
| Entrez Id: |
9132 |
| Gene Symbol: |
KCNQ4 |
KCNQ4
|
Nonsyndromic Deafness
|
0.390 |
Biomarker |
CLINGEN |
KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness.
|
10025409 |
1999 |
|
| Entrez Id: |
9132 |
| Gene Symbol: |
KCNQ4 |
KCNQ4
|
Nonsyndromic Deafness
|
0.390 |
Biomarker |
CLINGEN |
Mutations in the KCNQ4 gene are responsible for autosomal dominant deafness in four DFNA2 families.
|
10369879 |
1999 |
|
| Entrez Id: |
5456 |
| Gene Symbol: |
POU3F4 |
POU3F4
|
Nonsyndromic Deafness
|
0.340 |
Biomarker |
CLINGEN |
Targeted mutagenesis of the POU-domain gene Brn4/Pou3f4 causes developmental defects in the inner ear.
|
10407036 |
1999 |
|
| Entrez Id: |
7007 |
| Gene Symbol: |
TECTA |
TECTA
|
Nonsyndromic Deafness
|
0.330 |
Biomarker |
CLINGEN |
An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.
|
9949200 |
1999 |
|
| Entrez Id: |
3371 |
| Gene Symbol: |
TNC |
TNC
|
Nonsyndromic Deafness
|
0.310 |
Biomarker |
CLINGEN |
Tenascin-C in the cochlea of the developing mouse.
|
10102501 |
1999 |
|
| Entrez Id: |
51168 |
| Gene Symbol: |
MYO15A |
MYO15A
|
Nonsyndromic Deafness
|
0.480 |
Biomarker |
CLINGEN |
The motor and tail regions of myosin XV are critical for normal structure and function of auditory and vestibular hair cells.
|
10915760 |
2000 |
|
| Entrez Id: |
9132 |
| Gene Symbol: |
KCNQ4 |
KCNQ4
|
Nonsyndromic Deafness
|
0.390 |
Biomarker |
CLINGEN |
Longitudinal gradients of KCNQ4 expression in spiral ganglion and cochlear hair cells correlate with progressive hearing loss in DFNA2.
|
11042367 |
2000 |
|
| Entrez Id: |
5456 |
| Gene Symbol: |
POU3F4 |
POU3F4
|
Nonsyndromic Deafness
|
0.340 |
Biomarker |
CLINGEN |
The sex-linked fidget mutation abolishes Brn4/Pou3f4 gene expression in the embryonic inner ear.
|
10587581 |
2000 |
|
| Entrez Id: |
10083 |
| Gene Symbol: |
USH1C |
USH1C
|
Nonsyndromic Deafness
|
0.340 |
Biomarker |
CLINGEN |
As several of these transcripts were absent from the eye, we propose that USH1C also underlies the DFNB18 form of isolated deafness.
|
10973247 |
2000 |
|
| Entrez Id: |
7007 |
| Gene Symbol: |
TECTA |
TECTA
|
Nonsyndromic Deafness
|
0.330 |
Biomarker |
CLINGEN |
A targeted deletion in alpha-tectorin reveals that the tectorial membrane is required for the gain and timing of cochlear feedback.
|
11087000 |
2000 |
|
| Entrez Id: |
83715 |
| Gene Symbol: |
ESPN |
ESPN
|
Nonsyndromic Deafness
|
0.310 |
Biomarker |
CLINGEN |
The deaf jerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins.
|
10975527 |
2000 |
|
| Entrez Id: |
340990 |
| Gene Symbol: |
OTOG |
OTOG
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Targeted disruption of otog results in deafness and severe imbalance.
|
10655058 |
2000 |
|
| Entrez Id: |
375611 |
| Gene Symbol: |
SLC26A5 |
SLC26A5
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Prestin is the motor protein of cochlear outer hair cells.
|
10821263 |
2000 |