|
| Entrez Id: |
643226 |
| Gene Symbol: |
GRXCR2 |
GRXCR2
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Grxcr2 is required for stereocilia morphogenesis in the cochlea.
|
30157177 |
2018 |
|
| Entrez Id: |
9455 |
| Gene Symbol: |
HOMER2 |
HOMER2
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Whole exome sequencing identified a second pathogenic variant in HOMER2 for autosomal dominant non-syndromic deafness.
|
30047143 |
2018 |
|
| Entrez Id: |
124590 |
| Gene Symbol: |
USH1G |
USH1G
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Novel digenic inheritance of PCDH15 and USH1G underlies profound non-syndromic hearing impairment.
|
30029624 |
2018 |
|
| Entrez Id: |
23562 |
| Gene Symbol: |
CLDN14 |
CLDN14
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Measurements of ionic concentrations along with endocochlear potential in wild-type and claudin 14 knockout mice.
|
28811056 |
2018 |
|
| Entrez Id: |
643226 |
| Gene Symbol: |
GRXCR2 |
GRXCR2
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
GRXCR2 Regulates Taperin Localization Critical for Stereocilia Morphology and Hearing.
|
30380417 |
2018 |
|
| Entrez Id: |
84059 |
| Gene Symbol: |
ADGRV1 |
ADGRV1
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Recurrent variants in OTOF are significant contributors to prelingual nonsydromic hearing loss in Saudi patients.
|
29048421 |
2018 |
|
| Entrez Id: |
64787 |
| Gene Symbol: |
EPS8L2 |
EPS8L2
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Molecular Analysis of Twelve Pakistani Families with Nonsyndromic or Syndromic Hearing Loss.
|
28281779 |
2017 |
|
| Entrez Id: |
340990 |
| Gene Symbol: |
OTOG |
OTOG
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Delayed Otolith Development Does Not Impair Vestibular Circuit Formation in Zebrafish.
|
28332011 |
2017 |
|
| Entrez Id: |
80736 |
| Gene Symbol: |
SLC44A4 |
SLC44A4
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
SLC44A4 mutation causes autosomal dominant hereditary postlingual non-syndromic mid-frequency hearing loss.
|
28013291 |
2017 |
|
| Entrez Id: |
84059 |
| Gene Symbol: |
ADGRV1 |
ADGRV1
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Novel compound heterozygous mutations in the GPR98 (USH2C) gene identified by whole exome sequencing in a Moroccan deaf family.
|
28951997 |
2017 |
|
| Entrez Id: |
23562 |
| Gene Symbol: |
CLDN14 |
CLDN14
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
A common variant in CLDN14 causes precipitous, prelingual sensorineural hearing loss in multiple families due to founder effect.
|
27838790 |
2017 |
|
| Entrez Id: |
375611 |
| Gene Symbol: |
SLC26A5 |
SLC26A5
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Comprehensive genetic testing in the clinical evaluation of 1119 patients with hearing loss.
|
26969326 |
2016 |
|
| Entrez Id: |
124590 |
| Gene Symbol: |
USH1G |
USH1G
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
This is the first family presented with nonsyndromic hearing loss caused by mutations in USH1G.
|
25255398 |
2016 |
|
| Entrez Id: |
84059 |
| Gene Symbol: |
ADGRV1 |
ADGRV1
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
DNA Diagnostics of Hereditary Hearing Loss: A Targeted Resequencing Approach Combined with a Mutation Classification System.
|
27068579 |
2016 |
|
| Entrez Id: |
4919 |
| Gene Symbol: |
ROR1 |
ROR1
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice.
|
27162350 |
2016 |
|
| Entrez Id: |
152137 |
| Gene Symbol: |
CCDC50 |
CCDC50
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Comprehensive Genetic Analysis of Japanese Autosomal Dominant Sensorineural Hearing Loss Patients.
|
27911912 |
2016 |
|
| Entrez Id: |
54084 |
| Gene Symbol: |
TSPEAR |
TSPEAR
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
|
27736875 |
2016 |
|
| Entrez Id: |
124590 |
| Gene Symbol: |
USH1G |
USH1G
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Comprehensive analysis via exome sequencing uncovers genetic etiology in autosomal recessive nonsyndromic deafness in a large multiethnic cohort.
|
26226137 |
2016 |
|
| Entrez Id: |
124590 |
| Gene Symbol: |
USH1G |
USH1G
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Comprehensive genetic testing in the clinical evaluation of 1119 patients with hearing loss.
|
26969326 |
2016 |
|
| Entrez Id: |
9750 |
| Gene Symbol: |
RIPOR2 |
RIPOR2
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.
|
27269051 |
2016 |
|
| Entrez Id: |
146183 |
| Gene Symbol: |
OTOA |
OTOA
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Comprehensive genetic testing in the clinical evaluation of 1119 patients with hearing loss.
|
26969326 |
2016 |
|
| Entrez Id: |
54084 |
| Gene Symbol: |
TSPEAR |
TSPEAR
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Comprehensive genetic testing in the clinical evaluation of 1119 patients with hearing loss.
|
26969326 |
2016 |
|
| Entrez Id: |
375611 |
| Gene Symbol: |
SLC26A5 |
SLC26A5
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Overlapping expression of anion exchangers in the cochlea of a non-human primate suggests functional compensation.
|
27091614 |
2016 |
|
| Entrez Id: |
79977 |
| Gene Symbol: |
GRHL2 |
GRHL2
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Distinct Expression Patterns Of Causative Genes Responsible For Hereditary Progressive Hearing Loss In Non-Human Primate Cochlea.
|
26915689 |
2016 |
|
| Entrez Id: |
23562 |
| Gene Symbol: |
CLDN14 |
CLDN14
|
Nonsyndromic Deafness
|
0.300 |
Biomarker |
CLINGEN |
Targeted Resequencing of Deafness Genes Reveals a Founder MYO15A Variant in Northeastern Brazil.
|
27870113 |
2016 |