Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 81631
Gene Symbol: MAP1LC3B
MAP1LC3B
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers. 12371906

2003

Entrez Id: 5606
Gene Symbol: MAP2K3
MAP2K3
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Activation of ASK1, downstream MAPKK and MAPK isoforms during cardiac ischaemia. 20550965

2010

Entrez Id: 5837
Gene Symbol: PYGM
PYGM
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Alteration of glycogen and glucose metabolism in ischaemic and post-ischaemic working rat hearts by adenosine A1 receptor stimulation. 10498852

1999

Entrez Id: 1410
Gene Symbol: CRYAB
CRYAB
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Binding of alpha B-crystallin to titin during cardiac ischemia could serve to stabilize titin against denaturation and might provide an endogenous mechanism to delay ischemic damage of this important elastic component of myofibrils. 11945023

2002

Entrez Id: 958
Gene Symbol: CD40
CD40
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Therapeutic RGD Buyanghuanwu Decoction has a protective effect on myocardial ischemia induced by isoproterenol in rats, and it may be relevant to the decrease of the expression of CD40-CD40L and the activities of myocardial enzymes. 19565716

2009

Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Therapeutic RGD Buyanghuanwu Decoction has a protective effect on myocardial ischemia induced by isoproterenol in rats, and it may be relevant to the decrease of the expression of CD40-CD40L and the activities of myocardial enzymes. 19565716

2009

Entrez Id: 5534
Gene Symbol: PPP3R1
PPP3R1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.500 Biomarker RGD Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study. 16214533

2005

Entrez Id: 51738
Gene Symbol: GHRL
GHRL
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 ModifyingMutation RGD Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats. 16626506

2006

Entrez Id: 2693
Gene Symbol: GHSR
GHSR
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats. 16626506

2006

Entrez Id: 4015
Gene Symbol: LOX
LOX
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Differential regulation of functional gene clusters in overt coronary artery disease in a transgenic atherosclerosis-hypertensive rat model. 12393934

2002

Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Dual mechanism of autoregulation of protein kinase C in myocardial ischemia. 16924416

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.230 Therapeutic RGD Effect of curcumin on permeability of coronary artery and expression of related proteins in rat coronary atherosclerosis heart disease model. 26261622

2015

Entrez Id: 3764
Gene Symbol: KCNJ8
KCNJ8
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.500 Biomarker RGD Effect of electronic stimulation at Neiguan (PC 6) acupoint on gene expression of adenosine triphosphate-sensitive potassium channel and protein kinases in rats with myocardial ischemia. 26591689

2015

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Effect of electronic stimulation at Neiguan (PC 6) acupoint on gene expression of adenosine triphosphate-sensitive potassium channel and protein kinases in rats with myocardial ischemia. 26591689

2015

Entrez Id: 91
Gene Symbol: ACVR1B
ACVR1B
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Elevated levels of activin A in heart failure: potential role in myocardial remodeling. 14993131

2004

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.300 Biomarker RGD Establishment of a rat model with diet-induced coronary atherosclerosis. 28808185

2016

Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.560 Therapeutic RGD Ex vivo blockade of endothelin-1 inhibits graft coronary artery disease in a rodent cardiac allograft model. 11927217

2002

Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Functional study of TREK-1 potassium channels during rat heart development and cardiac ischemia using RNAi techniques. 24705172

2014

Entrez Id: 10628
Gene Symbol: TXNIP
TXNIP
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.220 Biomarker RGD Here, we report that VDUP1 expression is significantly increased in rat hearts following acute myocardial ischemia, suggesting it may have important regulatory effects on cardiac physiological processes during periods of oxidative stress. 16172122

2005

Entrez Id: 5179
Gene Symbol: PENK
PENK
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Therapeutic RGD HPLC/MS/MS for quantification of two types of neurotransmitters in rat brain and application: myocardial ischemia and protection of Sheng-Mai-San. 21247719

2011

Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.520 Biomarker RGD Hyperglycemia in streptozotocin-induced diabetic rat increases infarct size associated with low levels of myocardial HO-1 during ischemia/reperfusion. 15734859

2005

Entrez Id: 1981
Gene Symbol: EIF4G1
EIF4G1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Inhibition of Cap-initiation complexes linked to a novel mechanism of eIF4G depletion in acute myocardial ischemia. 16439989

2006

Entrez Id: 1977
Gene Symbol: EIF4E
EIF4E
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Inhibition of Cap-initiation complexes linked to a novel mechanism of eIF4G depletion in acute myocardial ischemia. 16439989

2006

Entrez Id: 1978
Gene Symbol: EIF4EBP1
EIF4EBP1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Inhibition of Cap-initiation complexes linked to a novel mechanism of eIF4G depletion in acute myocardial ischemia. 16439989

2006

Entrez Id: 1234
Gene Symbol: CCR5
CCR5
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Biomarker RGD Inhibition of chemokine receptor CCR2 and CCR5 expression contributes to simvastatin-induced attenuation of cardiac allograft vasculopathy. 17449418

2007