Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.600 Biomarker RGD [Preliminary investigation of the changes and mechanism of Leptin after myocardial ischemia/reperfusion injury]. 21122204

2010

Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.560 Therapeutic RGD Ex vivo blockade of endothelin-1 inhibits graft coronary artery disease in a rodent cardiac allograft model. 11927217

2002

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.550 Biomarker RGD Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. 16698918

2006

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.550 Biomarker RGD Prolonged cold ischemia in rat cardiac allografts promotes ischemia-reperfusion injury and the development of graft coronary artery disease in a linear fashion. 16297799

2005

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.550 Biomarker RGD Neutralization of MCAF/MCP-1 is beneficial by preventing reperfusion injury in a rat model of myocardial ischemia and reperfusion. 10068207

1999

Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.520 Biomarker RGD Hyperglycemia in streptozotocin-induced diabetic rat increases infarct size associated with low levels of myocardial HO-1 during ischemia/reperfusion. 15734859

2005

Entrez Id: 3764
Gene Symbol: KCNJ8
KCNJ8
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.500 Biomarker RGD Effect of electronic stimulation at Neiguan (PC 6) acupoint on gene expression of adenosine triphosphate-sensitive potassium channel and protein kinases in rats with myocardial ischemia. 26591689

2015

Entrez Id: 5534
Gene Symbol: PPP3R1
PPP3R1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.500 Biomarker RGD Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study. 16214533

2005

Entrez Id: 952
Gene Symbol: CD38
CD38
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.500 Biomarker RGD Myocardial ischemia and reperfusion reduce the levels of cyclic ADP-ribose in rat myocardium. 12111041

2002

Entrez Id: 3764
Gene Symbol: KCNJ8
KCNJ8
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.500 Biomarker RGD Myocardial ischemia induces differential regulation of KATP channel gene expression in rat hearts. 9399952

1997

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.300 Biomarker RGD Establishment of a rat model with diet-induced coronary atherosclerosis. 28808185

2016

Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.300 Biomarker RGD Regularity of hypoxia inducible factor 1 alpha expression in acute myocardial ischaemia in rats. 17335664

2007

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.240 Therapeutic RGD Protective effects of Carthamus tinctorius injection on isoprenaline-induced myocardial injury in rats. 22014268

2011

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.230 Therapeutic RGD Effect of curcumin on permeability of coronary artery and expression of related proteins in rat coronary atherosclerosis heart disease model. 26261622

2015

Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.230 Biomarker RGD Thus, pharmacologic enhancement of ALDH2 activity may be useful for patients with wild-type or mutant ALDH2 who are subjected to cardiac ischemia, such as during coronary bypass surgery. 18787169

2008

Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.230 Biomarker RGD Redox activation of aldose reductase in the ischemic heart. 16567803

2006

Entrez Id: 6649
Gene Symbol: SOD3
SOD3
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.220 Biomarker RGD Vascular effects of a common gene variant of extracellular superoxide dismutase in heart failure. 16840738

2006

Entrez Id: 10628
Gene Symbol: TXNIP
TXNIP
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.220 Biomarker RGD Here, we report that VDUP1 expression is significantly increased in rat hearts following acute myocardial ischemia, suggesting it may have important regulatory effects on cardiac physiological processes during periods of oxidative stress. 16172122

2005

Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.220 Biomarker RGD Purification of cardiac annexin V from the beagle dog heart and changes in its localization in the ischemic rat heart. 8056721

1994

Entrez Id: 9927
Gene Symbol: MFN2
MFN2
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.210 Therapeutic RGD Vagal nerve stimulation improves mitochondrial dynamics via an M3 receptor/CaMKKβ/AMPK pathway in isoproterenol-induced myocardial ischaemia. 27491814

2017

Entrez Id: 6424
Gene Symbol: SFRP4
SFRP4
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.210 Biomarker RGD Secreted frizzled related protein 4 reduces fibrosis scar size and ameliorates cardiac function after ischemic injury. 20528676

2010

Entrez Id: 6548
Gene Symbol: SLC9A1
SLC9A1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.210 Biomarker RGD The rise of [Na(+)] (i) during ischemia and reperfusion in the rat heart-underlying mechanisms. 17356886

2007

Entrez Id: 5348
Gene Symbol: FXYD1
FXYD1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.210 Biomarker RGD Ischemia-induced phosphorylation of phospholemman directly activates rat cardiac Na/K-ATPase. 14597563

2004

Entrez Id: 4151
Gene Symbol: MB
MB
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.210 Biomarker RGD The contrast of immunohistochemical studies of myocardial fibrinogen and myoglobin in early myocardial ischemia in rats. 12935692

2002

Entrez Id: 55669
Gene Symbol: MFN1
MFN1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia
0.200 Therapeutic RGD Vagal nerve stimulation improves mitochondrial dynamics via an M3 receptor/CaMKKβ/AMPK pathway in isoproterenol-induced myocardial ischaemia. 27491814

2017