×
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
RGD
The insulin-melatonin antagonism: studies in the LEW.1AR1-iddm rat (an animal model of human type 1 diabetes mellitus).
21491159 2011
×
Entrez Id: 199
Gene Symbol: AIF1
AIF1
Diabetes Mellitus, Insulin-Dependent
0.240
ModifyingMutation
RGD
Identification, isolation, and characterization of daintain (allograft inflammatory factor 1), a macrophage polypeptide with effects on insulin secretion and abundantly present in the pancreas of prediabetic BB rats.
9391121 1997
×
Entrez Id: 345
Gene Symbol: APOC3
APOC3
Diabetes Mellitus, Insulin-Dependent
0.270
Biomarker
RGD
Lowering apolipoprotein CIII delays onset of type 1 diabetes.
21670290 2011
×
Entrez Id: 100506742
Gene Symbol: CASP12
CASP12
Diabetes Mellitus, Insulin-Dependent
0.500
Biomarker
RGD
The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 diabetic rats.
15855338 2005
×
Entrez Id: 836
Gene Symbol: CASP3
CASP3
Diabetes Mellitus, Insulin-Dependent
0.290
Biomarker
RGD
The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 diabetic rats.
15855338 2005
×
Entrez Id: 867
Gene Symbol: CBL
CBL
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
RGD
Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat.
17082646 2006
×
Entrez Id: 868
Gene Symbol: CBLB
CBLB
Diabetes Mellitus, Insulin-Dependent
0.250
SusceptibilityMutation
RGD
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus.
12118252 2002
×
Entrez Id: 868
Gene Symbol: CBLB
CBLB
Diabetes Mellitus, Insulin-Dependent
0.250
Biomarker
RGD
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus.
12118252 2002
×
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
Diabetes Mellitus, Insulin-Dependent
0.210
Biomarker
RGD
Nicotine exposure exacerbates development of cataracts in a type 1 diabetic rat model.
23049540 2012
×
Entrez Id: 1234
Gene Symbol: CCR5
CCR5
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
RGD
Immunoregulatory role of nitric oxide in Kilham rat virus-induced autoimmune diabetes in DR-BB rats.
15240727 2004
×
Entrez Id: 952
Gene Symbol: CD38
CD38
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
MGD
Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion.
16585549 2006
×
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
Diabetes Mellitus, Insulin-Dependent
0.230
Biomarker
RGD
Costimulation and autoimmune diabetes in BB rats.
16611325 2006
×
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
Diabetes Mellitus, Insulin-Dependent
0.230
Therapeutic
RGD
Prevention of autoimmune diabetes in the DRBB rat by CD40/154 blockade.
12419284 2002
×
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
MGD
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia.
10319860 1999
×
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
RGD
Type 1 diabetes is considered to be a Th1-dominant autoimmune disease, and a suppressive effect of CXCL10 neutralization on diabetes development has been reported in a cyclophosphamide-induced accelerated diabetes model through induction of beta cell proliferation.16339582 2005
×
Entrez Id: 81704
Gene Symbol: DOCK8
DOCK8
Diabetes Mellitus, Insulin-Dependent
0.210
Biomarker
RGD
A novel Dock8 gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes .
26363782 2015
×
Entrez Id: 1843
Gene Symbol: DUSP1
DUSP1
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
RGD
Blunting of the immediate-early gene and mitogenic response in hepatectomized type 1 diabetic animals.
7485483 1995
×
Entrez Id: 1869
Gene Symbol: E2F1
E2F1
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
MGD
Consistent with these observations, E2f1 homozygous mutant NOD mice were highly predisposed to the development of IDDM and SS.
15470032 2004
×
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
RGD
Decreased autophosphorylation of EGF receptor in insulin-deficient diabetic rats.
2833110 1988
×
Entrez Id: 356
Gene Symbol: FASLG
FASLG
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
RGD
A novel multimeric form of FasL modulates the ability of diabetogenic T cells to mediate type 1 diabetes in an adoptive transfer model.
17324464 2007
×
Entrez Id: 356
Gene Symbol: FASLG
FASLG
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
MGD
×
Entrez Id: 57818
Gene Symbol: G6PC2
G6PC2
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
×
Entrez Id: 2572
Gene Symbol: GAD2
GAD2
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
To investigate the role of glutamic acid decarboxylase 65 (GAD65 ) in the development of the Type 1 diabetes of non-obese diabetic (NOD) mice, we analysed and characterised NOD mice with targeted disruption of the GAD65 gene.
14676944 2004
×
Entrez Id: 51083
Gene Symbol: GAL
GAL
Diabetes Mellitus, Insulin-Dependent
0.210
Biomarker
RGD
We conclude that the selective damage to islet sympathetic nerve terminals seen in BB diabetic rats, rather than the systemic factors of diabetic hyperglycemia or insulin deficiency, causes the increased galanin expression observed in the CG of this animal model of type 1 diabetes .
16487586 2006
×
Entrez Id: 2688
Gene Symbol: GH1
GH1
Diabetes Mellitus, Insulin-Dependent
0.290
Biomarker
RGD
Growth hormone responsiveness in vivo and in vitro to growth hormone releasing factor in the spontaneously diabetic BB Wistar rat.
2888037 1987