Source: CTD_mouse

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0751408
Disease: Suffering, Physical
Suffering, Physical 		0.200 Therapeutic CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.200 Biomarker CTD_mouse The findings of these experiments suggested that in hyperlipidemia the expression and (or) the functional activity of P-glycoprotein was diminished, leading to greater hepatic and renal uptake of cyclosporine A, and renal cellular toxicity. 24502637

2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C1706412
Disease: Lipidemias
Lipidemias 		0.200 Biomarker CTD_mouse Effects of serum lipoproteins on cyclosporine A cellular uptake and renal toxicity in vitro. 24502637

2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.200 Biomarker CTD_mouse An antioxidant Trolox restores decreased oral absorption of cyclosporine A after liver ischemia-reperfusion through distinct mechanisms between CYP3A and P-glycoprotein in the small intestine. 22749977

2012
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0022333
Disease: Jacksonian Seizure
Jacksonian Seizure 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0234535
Disease: Clonic Seizures
Clonic Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0270824
Disease: Visual seizure
Visual seizure 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0270844
Disease: Tonic Seizures
Tonic Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0270846
Disease: Epileptic drop attack
Epileptic drop attack 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0422850
Disease: Seizures, Somatosensory
Seizures, Somatosensory 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0422852
Disease: Seizures, Auditory
Seizures, Auditory 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0422853
Disease: Olfactory seizure
Olfactory seizure 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0422854
Disease: Gustatory seizure
Gustatory seizure 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0422855
Disease: Vertiginous seizure
Vertiginous seizure 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0751056
Disease: Non-epileptic convulsion
Non-epileptic convulsion 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0751110
Disease: Single Seizure
Single Seizure 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0751123
Disease: Atonic Absence Seizures
Atonic Absence Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0751494
Disease: Convulsive Seizures
Convulsive Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0751495
Disease: Seizures, Focal
Seizures, Focal 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0751496
Disease: Seizures, Sensory
Seizures, Sensory 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C3495874
Disease: Nonepileptic Seizures
Nonepileptic Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C4317123
Disease: Myoclonic Seizures
Myoclonic Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C4505436
Disease: Generalized Absence Seizures
Generalized Absence Seizures 		0.200 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007