Source: CTD_mouse

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease 		0.540 Biomarker CTD_mouse Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. 26134275

2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0013221
Disease: Drug toxicity
Drug toxicity 		0.500 Biomarker CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0041755
Disease: Adverse reaction to drug
Adverse reaction to drug 		0.500 Biomarker CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0019193
Disease: Hepatitis, Toxic
Hepatitis, Toxic 		0.500 Biomarker CTD_mouse Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. 26134275

2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C1262760
Disease: Hepatitis, Drug-Induced
Hepatitis, Drug-Induced 		0.500 Biomarker CTD_mouse Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. 26134275

2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.500 Biomarker CTD_mouse Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. 26134275

2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Biomarker CTD_mouse Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. 26134275

2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity 		0.500 Biomarker CTD_mouse Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. 26134275

2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0013221
Disease: Drug toxicity
Drug toxicity 		0.500 Biomarker CTD_mouse Effects of serum lipoproteins on cyclosporine A cellular uptake and renal toxicity in vitro. 24502637

2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0041755
Disease: Adverse reaction to drug
Adverse reaction to drug 		0.500 Biomarker CTD_mouse Effects of serum lipoproteins on cyclosporine A cellular uptake and renal toxicity in vitro. 24502637

2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.500 Biomarker CTD_mouse Effects of hepatic fibrosis on ofloxacin pharmacokinetics in rats. 16182555

2006
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0030193
Disease: Pain
Pain 		0.300 Therapeutic CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0036572
Disease: Seizures
Seizures 		0.300 Biomarker CTD_mouse Furthermore, our data suggest that TR(-) rats are an interesting tool to study consequences of overexpression of Pgp in the BBB on access of drugs in the brain, without the need of inducing seizures or other Pgp-enhancing events for this purpose. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.290 Biomarker CTD_mouse In the present study, Pgp expression was studied by immunohistochemistry in rats 24 h after a status epilepticus induced by either pilocarpine or kainate, widely used models of temporal lobe epilepsy. 14706787

2004
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.220 Biomarker CTD_mouse Effects of serum lipoproteins on cyclosporine A cellular uptake and renal toxicity in vitro. 24502637

2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0149958
Disease: Complex partial seizures
Complex partial seizures 		0.210 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0234533
Disease: Generalized seizures
Generalized seizures 		0.210 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0494475
Disease: Tonic - clonic seizures
Tonic - clonic seizures 		0.210 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C4048158
Disease: Convulsions
Convulsions 		0.210 Biomarker CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408

2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0234230
Disease: Pain, Burning
Pain, Burning 		0.200 Therapeutic CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0234238
Disease: Ache
Ache 		0.200 Therapeutic CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0234254
Disease: Radiating pain
Radiating pain 		0.200 Therapeutic CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0458257
Disease: Pain, Splitting
Pain, Splitting 		0.200 Therapeutic CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0458259
Disease: Pain, Crushing
Pain, Crushing 		0.200 Therapeutic CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0751407
Disease: Pain, Migratory
Pain, Migratory 		0.200 Therapeutic CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520

2017