Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD The chronological characteristics of SOD1 activity and inflammatory response in the hippocampi of STZ-induced type 1 diabetic rats. 20924670

2011

Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Therapeutic RGD The effects of resveratrol on cyclooxygenase-1 and -2, nuclear factor kappa beta, matrix metalloproteinase-9, and sirtuin 1 mRNA expression in hearts of streptozotocin-induced diabetic rats. 22179968

2011

Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 ModifyingMutation RGD Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats. 20695765

2011

Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD IL-2 and IFN-gamma in the retina of diabetic rats. 20213480

2010

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Regulation of IRS-2 signaling by IGF-1 receptor in the diabetic rat heart. 20555424

2010

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Engineered zinc finger protein-mediated VEGF-a activation restores deficient VEGF-a in sensory neurons in experimental diabetes. 19934008

2010

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Regulation of IRS-2 signaling by IGF-1 receptor in the diabetic rat heart. 20555424

2010

Entrez Id: 155
Gene Symbol: ADRB3
ADRB3
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Intense exercise training induces adaptation in expression and responsiveness of cardiac β-adrenoceptors in diabetic rats. 21054861

2010

Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Therapeutic RGD Aldose reductase inhibitor fidarestat attenuates leukocyte-endothelial interactions in experimental diabetic rat retina in vivo. 20136425

2010

Entrez Id: 2936
Gene Symbol: GSR
GSR
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Beneficial effect of xylo-oligosaccharides and fructo-oligosaccharides in streptozotocin-induced diabetic rats. 20187988

2010

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Regulation of IRS-2 signaling by IGF-1 receptor in the diabetic rat heart. 20555424

2010

Entrez Id: 8660
Gene Symbol: IRS2
IRS2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Regulation of IRS-2 signaling by IGF-1 receptor in the diabetic rat heart. 20555424

2010

Entrez Id: 489
Gene Symbol: ATP2A3
ATP2A3
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Intracellular Ca2+ regulating proteins in vascular smooth muscle cells are altered with type 1 diabetes due to the direct effects of hyperglycemia. 20122173

2010

Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Intracellular Ca2+ regulating proteins in vascular smooth muscle cells are altered with type 1 diabetes due to the direct effects of hyperglycemia. 20122173

2010

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Effects of rosiglitazone and aspirin on experimental model of induced type 2 diabetes in rats: focus on insulin resistance and inflammatory markers. 19328014

2010

Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Diabetic rat testes: morphological and functional alterations. 19891634

2009

Entrez Id: 6514
Gene Symbol: SLC2A2
SLC2A2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD SLC2A2 gene expression in kidney of diabetic rats is regulated by HNF-1alpha and HNF-3beta. 19433262

2009

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD The timing of re-institution of good blood glucose control affects apoptosis and expression of Bax and Bcl-2 in the retina of diabetic rats. 18991018

2009

Entrez Id: 2876
Gene Symbol: GPX1
GPX1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Gene expressions of Mn-SOD and GPx-1 in streptozotocin-induced diabetes: effect of antioxidants. 19229592

2009

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats. 18976114

2009

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Therapeutic RGD Effects of probucol on hepatic tumor necrosis factor-alpha, interleukin-6 and adiponectin receptor-2 expression in diabetic rats. 19220660

2009

Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD A functional melanocortin system may be required for chronic CNS-mediated antidiabetic and cardiovascular actions of leptin. 19491210

2009

Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD The timing of re-institution of good blood glucose control affects apoptosis and expression of Bax and Bcl-2 in the retina of diabetic rats. 18991018

2009

Entrez Id: 8639
Gene Symbol: AOC3
AOC3
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Vascular adhesion protein-1 regulates leukocyte transmigration rate in the retina during diabetes. 19635478

2009

Entrez Id: 7351
Gene Symbol: UCP2
UCP2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Identification and distribution of uncoupling protein isoforms in the normal and diabetic rat kidney. 19227473

2009