×
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
Parkinson Disease
0.570
Biomarker
RGD
Loss of synaptic D1 dopamine/N-methyl-D-aspartate glutamate receptor complexes in L-DOPA-induced dyskinesia in the rat.
16365282 2006
×
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
Parkinson Disease
0.600
Biomarker
RGD
Modification of L-DOPA pharmacological activity by MAO inhibitors.
17417741 2007
×
Entrez Id: 3312
Gene Symbol: HSPA8
HSPA8
Parkinson Disease
0.300
Biomarker
RGD
In vivo induction of heat shock proteins in the substantia nigra following L-DOPA administration is associated with increased activity of mitochondrial complex I and nitrosative stress in rats: regulation by glutathione redox state.
17241115 2007
×
Entrez Id: 3952
Gene Symbol: LEP
LEP
Parkinson Disease
0.210
Therapeutic
RGD
Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling.
17895242 2007
×
Entrez Id: 356
Gene Symbol: FASLG
FASLG
Parkinson Disease
0.200
Biomarker
RGD
Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease.
17959308 2007
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Parkinson Disease
0.600
Biomarker
RGD
Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats.
18289173 2008
×
Entrez Id: 6697
Gene Symbol: SPR
SPR
Parkinson Disease
0.260
Biomarker
MGD
A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase -null mice--as a mouse model for Parkinson's disease .
18201550 2008
×
Entrez Id: 2869
Gene Symbol: GRK5
GRK5
Parkinson Disease
0.230
Biomarker
RGD
Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
17996024 2008
×
Entrez Id: 84687
Gene Symbol: PPP1R9B
PPP1R9B
Parkinson Disease
0.220
Biomarker
RGD
Association of protein phosphatase 1 gamma 1 with spinophilin suppresses phosphatase activity in a Parkinson disease model.
18372251 2008
×
Entrez Id: 2870
Gene Symbol: GRK6
GRK6
Parkinson Disease
0.210
Biomarker
RGD
Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
17996024 2008
×
Entrez Id: 157
Gene Symbol: GRK3
GRK3
Parkinson Disease
0.200
Biomarker
RGD
Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
17996024 2008
×
Entrez Id: 156
Gene Symbol: GRK2
GRK2
Parkinson Disease
0.200
Biomarker
RGD
Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
17996024 2008
×
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
Parkinson Disease
0.510
Biomarker
RGD
Ginsenoside Rg1 protects dopaminergic neurons in a rat model of Parkinson's disease through the IGF-I receptor signalling pathway.
19703168 2009
×
Entrez Id: 5764
Gene Symbol: PTN
PTN
Parkinson Disease
0.210
Therapeutic
RGD
Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons.
19615368 2009
×
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
Parkinson Disease
0.200
Biomarker
RGD
Increased MMP-3 and CTGF expression during lipopolysaccharide-induced dopaminergic neurodegeneration.
19463894 2009
×
Entrez Id: 57657
Gene Symbol: HCN3
HCN3
Parkinson Disease
0.200
Biomarker
RGD
Our cell-type selective transcriptome analyses of BGON in the rat 6-hydroxydopamine (6-OHDA) model of PD identified the ion channel HCN3 as a likely contributor to altered neuronal excitability.
19320057 2009
×
Entrez Id: 5309
Gene Symbol: PITX3
PITX3
Parkinson Disease
0.300
Biomarker
MGD
Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice.
20033184 2010
×
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
Parkinson Disease
0.230
Biomarker
RGD
Our study indicates that buspirone improves catalepsy in a 6-OHDA-induced animal model of Parkinson's disease through activation of nigral 5-HT(1A ) receptors.
20508280 2010
×
Entrez Id: 10094
Gene Symbol: ARPC3
ARPC3
Parkinson Disease
0.200
Therapeutic
RGD
Antiparkinsonian trophic action of glial cell line-derived neurotrophic factor and transforming growth factor β1 is enhanced after co-infusion in rats.
20713051 2010
×
Entrez Id: 6571
Gene Symbol: SLC18A2
SLC18A2
Parkinson Disease
0.600
Biomarker
RGD
Protective effect of Zhen-Wu-Tang (ZWT) through keeping DA stable and VMAT 2/DAT mRNA in balance in rats with striatal lesions induced by MPTP.
21291984 2011
×
Entrez Id: 7054
Gene Symbol: TH
TH
Parkinson Disease
0.600
Biomarker
RGD
Protective effect of resveratrol derived from Polygonum cuspidatum and its liposomal form on nigral cells in parkinsonian rats.
21376343 2011
×
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4
Parkinson Disease
0.300
Biomarker
RGD
Mildronate as a regulator of protein expression in a rat model of Parkinson's disease.
22186119 2011
×
Entrez Id: 131
Gene Symbol: ADH7
ADH7
Parkinson Disease
0.220
Biomarker
MGD
Modeling Parkinson's disease genetics: altered function of the dopamine system in Adh4 knockout mice.
21075145 2011
×
Entrez Id: 4537
Gene Symbol: ND3
ND3
Parkinson Disease
0.210
Biomarker
RGD
Protective effect of lycopene on oxidative stress and cognitive decline in rotenone induced model of Parkinson's disease.
21484267 2011
×
Entrez Id: 57165
Gene Symbol: GJC2
GJC2
Parkinson Disease
0.200
Therapeutic
RGD
Nigrostriatal proteomics of cypermethrin-induced dopaminergic neurodegeneration: microglial activation-dependent and -independent regulations.
21561882 2011