×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.900
Biomarker
RGD
Key mechanisms underlying netrin-1 prevention of impaired spatial and object memory in Aβ1-42 CA1-injected rats.
30066400
2019
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.900
Biomarker
RGD
Intracerebroventricular streptozotocin impairs adult neurogenesis and cognitive functions via regulating neuroinflammation and insulin signaling in adult rats.
29174383
2018
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.900
Therapeutic
RGD
Inhibition of endothelial nitric oxide synthase reverses the effect of exercise on improving cognitive function in hypertensive rats.
29568075
2018
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Alzheimer's Disease
0.900
Biomarker
RGD
In this study, we explore the effects of altered angiotensin-converting enzyme (ACE), and investigate the possible mechanisms of perindopril, an ACE inhibitor, on brain structure and function in a rat model of AD , as well as the role that ACE plays in AD .
19080340
2008
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.900
Biomarker
MGD
×
Entrez Id:
2932
Gene Symbol:
GSK3B
GSK3B
Alzheimer's Disease
0.700
Therapeutic
RGD
Vildagliptin prevents cognitive deficits and neuronal apoptosis in a rat model of Alzheimer's disease.
29257340
2018
×
Entrez Id:
4137
Gene Symbol:
MAPT
MAPT
Alzheimer's Disease
0.700
Biomarker
RGD
Involvement of glucose related energy crisis and endoplasmic reticulum stress: Insinuation of streptozotocin induced Alzheimer's like pathology.
29126976
2018
×
Entrez Id:
4137
Gene Symbol:
MAPT
MAPT
Alzheimer's Disease
0.700
Therapeutic
RGD
A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model.
28342971
2017
×
Entrez Id:
4137
Gene Symbol:
MAPT
MAPT
Alzheimer's Disease
0.700
Therapeutic
RGD
Antioxidative and Neuroprotective Effects of Curcumin in an Alzheimer's Disease Rat Model Co-Treated with Intracerebroventricular Streptozotocin and Subcutaneous D-Galactose.
27060945
2016
×
Entrez Id:
2932
Gene Symbol:
GSK3B
GSK3B
Alzheimer's Disease
0.700
Therapeutic
RGD
Fenugreek Seed Powder Nullified Aluminium Chloride Induced Memory Loss, Biochemical Changes, Aβ Burden and Apoptosis via Regulating Akt/GSK3β Signaling Pathway.
27893738
2016
×
Entrez Id:
102
Gene Symbol:
ADAM10
ADAM10
Alzheimer's Disease
0.700
Biomarker
RGD
Effects of aluminium on β-amyloid (1-42) and secretases (APP-cleaving enzymes) in rat brain.
24792732
2014
×
Entrez Id:
102
Gene Symbol:
ADAM10
ADAM10
Alzheimer's Disease
0.700
Biomarker
RGD
Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo.
23296102
2013
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
Alzheimer's Disease
0.700
Biomarker
RGD
These results are consistent with a role for APOE in Aβ clearance in AD synapses, and suggest that optimal lipidation of apoE2 compared to E3 and E4 makes an important contribution to Aβ clearance and synaptic function.
22020632
2012
×
Entrez Id:
2932
Gene Symbol:
GSK3B
GSK3B
Alzheimer's Disease
0.700
Biomarker
RGD
Central angiotensin II-induced Alzheimer-like tau phosphorylation in normal rat brains.
22982863
2012
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
Alzheimer's Disease
0.700
Therapeutic
RGD
Red mold rice promotes neuroprotective sAPPalpha secretion instead of Alzheimer's risk factors and amyloid beta expression in hyperlipidemic Abeta40-infused rats.
20088507
2010
×
Entrez Id:
5663
Gene Symbol:
PSEN1
PSEN1
Alzheimer's Disease
0.700
Biomarker
MGD
×
Entrez Id:
5328
Gene Symbol:
PLAU
PLAU
Alzheimer's Disease
0.680
Biomarker
MGD
×
Entrez Id:
836
Gene Symbol:
CASP3
CASP3
Alzheimer's Disease
0.600
Therapeutic
RGD
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease.
29777699
2018
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274
2018
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease.
29777699
2018
×
Entrez Id:
836
Gene Symbol:
CASP3
CASP3
Alzheimer's Disease
0.600
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274
2018
×
Entrez Id:
3416
Gene Symbol:
IDE
IDE
Alzheimer's Disease
0.600
Therapeutic
RGD
Treadmill Exercise Ameliorates Spatial Learning and Memory Deficits Through Improving the Clearance of Peripheral and Central Amyloid-Beta Levels.
29948724
2018
×
Entrez Id:
836
Gene Symbol:
CASP3
CASP3
Alzheimer's Disease
0.600
Therapeutic
RGD
Effects of Lignans from Schisandra chinensis Rattan Stems against Aβ
29642617
2018
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
Neuroprotective Effect of Nanodiamond in Alzheimer's Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling.
26897372
2017
×
Entrez Id:
3416
Gene Symbol:
IDE
IDE
Alzheimer's Disease
0.600
Therapeutic
RGD
Multifunctional Compound AD-35 Improves Cognitive Impairment and Attenuates the Production of TNF-α and IL-1β in an Aβ25-35-induced Rat Model of Alzheimer's Disease.
28157092
2017