| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
transthyretin | 0.423 | 0.885 | 0.52 |
|
disease | 0.500 | None | 0.985 | 477 | 24 | 1981 | 2020 | ||||||||
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.400 | None | 0.981 | 266 | 8 | 1988 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.400 | None | 0.955 | 131 | 0 | 1995 | 2020 | ||||||||
|
gelsolin | 0.475 | 0.885 | 3.9E-11 |
|
disease | 0.400 | strong | 1.000 | 50 | 6 | 1990 | 2020 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.400 | None | 1.000 | 37 | 2 | 1997 | 2020 | ||||||||
|
acetylcholinesterase (Cartwright blood group) | 0.445 | 0.885 | 1.00 |
|
disease | 0.400 | None | 1.000 | 16 | 0 | 1996 | 2020 | ||||||||
|
heme oxygenase 1 | 0.381 | 0.923 | 9.7E-03 |
|
disease | 0.320 | limited | 1.000 | 2 | 0 | 2011 | 2018 | ||||||||
|
apolipoprotein C3 | 0.531 | 0.731 | 1.0E-02 |
|
disease | 0.310 | moderate | < 0.001 | 1 | 0 | 2016 | 2016 | ||||||||
|
TNF receptor superfamily member 1A | 0.409 | 0.923 | 0.99 |
|
disease | 0.140 | None | 1.000 | 3 | 2 | 2002 | 2018 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
DNA polymerase alpha 1, catalytic subunit | 0.653 | 0.731 | 1.00 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.100 | None | 0.938 | 64 | 0 | 1990 | 2020 | ||||||||
|
beta-secretase 1 | 0.559 | 0.769 | 0.88 |
|
disease | 0.100 | None | 1.000 | 52 | 0 | 2005 | 2019 | ||||||||
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.100 | None | 1.000 | 40 | 0 | 1993 | 2020 | ||||||||
|
apolipoprotein A1 | 0.429 | 0.885 | 5.5E-04 |
|
disease | 0.100 | None | 0.950 | 39 | 1 | 1998 | 2019 | ||||||||
|
colony stimulating factor 2 | 0.330 | 0.962 | 0.83 |
|
disease | 0.100 | None | 1.000 | 37 | 0 | 2017 | 2020 | ||||||||
|
laminin subunit gamma 2 | 0.389 | 0.923 | 2.9E-12 |
|
disease | 0.100 | None | 1.000 | 37 | 0 | 2017 | 2020 | ||||||||
|
prion protein | 0.445 | 0.923 | 6.3E-04 |
|
disease | 0.100 | None | 0.941 | 34 | 1 | 1993 | 2019 | ||||||||
|
MEFV innate immuity regulator, pyrin | 0.440 | 0.885 | 1.0E-14 |
|
disease | 0.100 | None | 0.941 | 32 | 6 | 1998 | 2019 | ||||||||
|
serum amyloid A1 | 0.513 | 0.808 | 1.5E-02 |
|
disease | 0.100 | None | 0.971 | 32 | 1 | 1986 | 2019 | ||||||||
|
islet amyloid polypeptide | 0.507 | 0.808 | 3.2E-03 |
|
disease | 0.100 | None | 0.968 | 30 | 1 | 1994 | 2020 | ||||||||
|
lysozyme | 0.526 | 0.846 | 3.4E-06 |
|
disease | 0.100 | None | 1.000 | 24 | 5 | 1988 | 2019 | ||||||||
|
membrane metalloendopeptidase | 0.407 | 0.808 | 1.5E-18 |
|
disease | 0.100 | None | 0.955 | 21 | 0 | 2003 | 2019 | ||||||||
|
beta-2-microglobulin | 0.447 | 0.846 | 0.56 |
|
disease | 0.100 | None | 0.955 | 20 | 0 | 1996 | 2020 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.100 | None | 0.947 | 19 | 2 | 2011 | 2019 |