Source: ORPHANET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.700 SusceptibilityMutation ORPHANET Interleukin-10 gene polymorphisms are associated with Behcet's disease but not with Vogt-Koyanagi-Harada syndrome in the Chinese Han population. 26015771

2015
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.700 SusceptibilityMutation ORPHANET Brief report: association of CCR1, KLRC4, IL12A-AS1, STAT4, and ERAP1 With Behçet's disease in Iranians. 26097239

2015
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.700 SusceptibilityMutation ORPHANET Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878

2010
Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.700 SusceptibilityMutation ORPHANET Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878

2010
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.670 SusceptibilityMutation ORPHANET Brief report: association of CCR1, KLRC4, IL12A-AS1, STAT4, and ERAP1 With Behçet's disease in Iranians. 26097239

2015
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.670 SusceptibilityMutation ORPHANET Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study. 23001997

2012
Entrez Id: 8302
Gene Symbol: KLRC4
KLRC4
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.630 SusceptibilityMutation ORPHANET Brief report: association of CCR1, KLRC4, IL12A-AS1, STAT4, and ERAP1 With Behçet's disease in Iranians. 26097239

2015
Entrez Id: 1230
Gene Symbol: CCR1
CCR1
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.540 SusceptibilityMutation ORPHANET Brief report: association of CCR1, KLRC4, IL12A-AS1, STAT4, and ERAP1 With Behçet's disease in Iranians. 26097239

2015
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.500 SusceptibilityMutation ORPHANET Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behçet disease. 23633568

2013
Entrez Id: 101928376
Gene Symbol: IL12A-AS1
IL12A-AS1
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.410 SusceptibilityMutation ORPHANET Brief report: association of CCR1, KLRC4, IL12A-AS1, STAT4, and ERAP1 With Behçet's disease in Iranians. 26097239

2015
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.400 SusceptibilityMutation ORPHANET Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behçet disease. 23633568

2013
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.400 SusceptibilityMutation ORPHANET Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behçet disease. 23633568

2013
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.340 SusceptibilityMutation ORPHANET The mRNA expression of UBAC2 transcript variant 1 was significantly decreased in PBMCs and skin of BD patients as compared with controls (P = 0.025; P = 0.047, respectively). 22455605

2012
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.340 SusceptibilityMutation ORPHANET A putative functional variant within the UBAC2 gene is associated with increased risk of Behçet's disease. 21918955

2011
Entrez Id: 3592
Gene Symbol: IL12A
IL12A
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.330 SusceptibilityMutation ORPHANET Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease. 25799145

2015
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.330 SusceptibilityMutation ORPHANET FAS Gene Copy Numbers are Associated with Susceptibility to Behçet Disease and VKH Syndrome in Han Chinese. 26136352

2015
Entrez Id: 720
Gene Symbol: C4A
C4A
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.300 SusceptibilityMutation ORPHANET Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis. 23918728

2013