Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD Early administration of propofol protects against endotoxin-induced acute lung injury in rats by inhibiting the TGF-beta1-Smad2 dependent pathway. 19941153

2010

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD Pyrrolidine dithiocarbamate attenuates paraquat-induced lung injury in rats. 19639047

2009

Entrez Id: 6439
Gene Symbol: SFTPB
SFTPB
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD [Expression of HoxB5 mRNA and their effect on lung development in premature rats with hyperoxia-induced chronic lung disease]. 19099817

2008

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD [Studies on the expression of mRNA of anti- and pro-inflammatory cytokines in acute lung injury induced by lipopolysaccharide in rat]. 15461830

2004

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD Ventilator-induced lung injury leads to loss of alveolar and systemic compartmentalization of tumor necrosis factor-alpha. 11126266

2000

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD Evidence of a central role for p38 map kinase induction of tumor necrosis factor alpha in pancreatitis-associated pulmonary injury. 10455887

1999

Entrez Id: 6439
Gene Symbol: SFTPB
SFTPB
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD Exudative lung injury is associated with decreased levels of surfactant proteins in a rat model of meconium aspiration. 9374572

1997

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.560 Biomarker RGD [Expression of angiotensin converting enzyme and angiotensin converting enzyme 2 gene in lung of paraquat poisoning rats and protection of sodium dimercaptopropane sulfonate]. 20465954

2010

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.560 Biomarker RGD Effects of an angiotensin-converting enzyme inhibitor on the inflammatory response in in vivo and in vitro models. 19114890

2009

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.300 Biomarker RGD A quantitative study of lung dysfunction following haemorrhagic shock in rats. 20041965

2010

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.300 Biomarker RGD Ghrelin attenuates acute pancreatitis-induced lung injury and inhibits substance P expression. 19926967

2010

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.300 Biomarker RGD Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in rats. 19843795

2009

Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.300 Biomarker RGD Relationship between pulmonary surfactant protein and lipid peroxidation in lung injury due to paraquat intoxication in rats. 17616020

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.290 Biomarker RGD Matrix metalloprotease expressions in both reperfusion lung injury and oleic acid lung injury models and the protective effects of ilomastat. 19545667

2009

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.290 Biomarker RGD Inhibition of matrix metalloproteinase-9 with doxycycline reduces pancreatitis-associated lung injury. 19494493

2009

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.290 Biomarker RGD Elevated transforming growth factor-alpha levels in bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome. 9700116

1998

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.280 Biomarker RGD Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis. 20709317

2011

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.280 ModifyingMutation RGD Recruitment maneuver in experimental acute lung injury: the role of alveolar collapse and edema. 20818231

2010

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.260 Biomarker RGD Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion. 19515386

2009

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.260 Biomarker RGD Production and effects of alpha-melanocyte-stimulating hormone during acute lung injury. 17304115

2007

Entrez Id: 653509
Gene Symbol: SFTPA1
SFTPA1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.260 Biomarker RGD Relationship between pulmonary surfactant protein and lipid peroxidation in lung injury due to paraquat intoxication in rats. 17616020

2007

Entrez Id: 653509
Gene Symbol: SFTPA1
SFTPA1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.260 Biomarker RGD Exudative lung injury is associated with decreased levels of surfactant proteins in a rat model of meconium aspiration. 9374572

1997

Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.250 Biomarker RGD [Expression of angiotensin converting enzyme and angiotensin converting enzyme 2 gene in lung of paraquat poisoning rats and protection of sodium dimercaptopropane sulfonate]. 20465954

2010

Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.250 Biomarker RGD [Effects of vasoactive intestinal peptide on Toll-like receptor (TLR) 2 mRNA and TLR4 mRNA expression on acute lung injury induced by lipopolysaccharide in rat]. 20441697

2010

Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.250 Biomarker RGD Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice. 19956717

2009