Source: MGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23414
Gene Symbol: ZFPM2
ZFPM2
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		1.000 Biomarker MGD Fog2 is required for normal diaphragm and lung development in mice and humans. 16103912

2005
Entrez Id: 23414
Gene Symbol: ZFPM2
ZFPM2
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		1.000 Biomarker MGD FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium. 10892744

2000
Entrez Id: 1482
Gene Symbol: NKX2-5
NKX2-5
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.960 Biomarker MGD Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling. 28352650

2017
Entrez Id: 2702
Gene Symbol: GJA5
GJA5
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.620 Biomarker MGD High incidence of cardiac malformations in connexin40-deficient mice. 12842919

2003
Entrez Id: 10370
Gene Symbol: CITED2
CITED2
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.610 Biomarker MGD The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation. 12149478

2002
Entrez Id: 2253
Gene Symbol: FGF8
FGF8
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.300 Biomarker MGD

Entrez Id: 23493
Gene Symbol: HEY2
HEY2
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.220 Biomarker MGD Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice. 12372254

2002
Entrez Id: 54903
Gene Symbol: MKS1
MKS1
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.210 Biomarker MGD Genome-wide identification of mouse congenital heart disease loci. 20511334

2010
Entrez Id: 4908
Gene Symbol: NTF3
NTF3
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development. 19755105

2009
Entrez Id: 1767
Gene Symbol: DNAH5
DNAH5
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia. 18037990

2007
Entrez Id: 1911
Gene Symbol: PHC1
PHC1
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis. 12122109

2002
Entrez Id: 1911
Gene Symbol: PHC1
PHC1
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells. 11901201

2002
Entrez Id: 4908
Gene Symbol: NTF3
NTF3
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice. 10681461

2000
Entrez Id: 27130
Gene Symbol: INVS
INVS
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD Situs variation and cardiovascular anomalies in the transgenic mouse insertional mutation, inv. 9664638

1998
Entrez Id: 1911
Gene Symbol: PHC1
PHC1
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects. 9367423

1997
Entrez Id: 4908
Gene Symbol: NTF3
NTF3
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD Absence of sensory neurons before target innervation in brain-derived neurotrophic factor-, neurotrophin 3-, and TrkC-deficient embryonic mice. 9364058

1997
Entrez Id: 4908
Gene Symbol: NTF3
NTF3
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD Identification of an essential nonneuronal function of neurotrophin 3 in mammalian cardiac development. 8841198

1996
Entrez Id: 4908
Gene Symbol: NTF3
NTF3
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons. 7991545

1994
Entrez Id: 27302
Gene Symbol: BMP10
BMP10
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD

Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot 		0.200 Biomarker MGD