| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
matrix Gla protein | 0.539 | 0.846 | 3.6E-05 |
|
phenotype | 0.400 | None | 1.000 | 37 | 2 | 1998 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
phenotype | 0.340 | None | 1.000 | 5 | 0 | 2013 | 2019 | ||||||||
|
parathyroid hormone | 0.397 | 0.846 | 1.2E-02 |
|
phenotype | 0.270 | None | 1.000 | 9 | 0 | 2012 | 2020 | ||||||||
|
TNF receptor superfamily member 11b | 0.422 | 0.808 | 0.16 |
|
phenotype | 0.100 | None | 0.960 | 25 | 0 | 2000 | 2019 | ||||||||
|
klotho | 0.448 | 0.769 | 2.2E-04 |
|
phenotype | 0.100 | None | 0.895 | 19 | 0 | 2003 | 2020 | ||||||||
|
fibroblast growth factor 23 | 0.460 | 0.731 | 3.1E-02 |
|
phenotype | 0.100 | None | 0.941 | 17 | 0 | 2005 | 2020 | ||||||||
|
alpha 2-HS glycoprotein | 0.506 | 0.846 | 3.2E-10 |
|
phenotype | 0.100 | None | 1.000 | 14 | 1 | 2005 | 2019 | ||||||||
|
RUNX family transcription factor 2 | 0.437 | 0.846 | 0.95 |
|
phenotype | 0.100 | None | 1.000 | 12 | 0 | 2003 | 2019 | ||||||||
|
bone gamma-carboxyglutamate protein | 0.462 | 0.846 | 4.6E-08 |
|
phenotype | 0.100 | None | 0.917 | 12 | 0 | 2006 | 2019 | ||||||||
|
bone morphogenetic protein 2 | 0.432 | 0.846 | 0.99 |
|
phenotype | 0.100 | None | 0.900 | 10 | 0 | 2006 | 2019 | ||||||||
|
polypeptide N-acetylgalactosaminyltransferase 3 | 0.603 | 0.769 | 7.4E-09 |
|
phenotype | 0.100 | None | 0 | 0 | |||||||||||
|
glucosylceramidase beta | 0.500 | 0.808 | 1.4E-06 |
|
phenotype | 0.100 | None | 0 | 0 | |||||||||||
|
POU class 1 homeobox 1 | 0.548 | 0.654 | 4.5E-02 |
|
phenotype | 0.080 | None | 1.000 | 8 | 0 | 2010 | 2019 | ||||||||
|
solute carrier family 20 member 1 | 0.582 | 0.577 | 6.7E-02 |
|
phenotype | 0.080 | None | 1.000 | 8 | 0 | 2010 | 2019 | ||||||||
|
secreted phosphoprotein 1 | 0.353 | 0.885 | 2.1E-06 |
|
phenotype | 0.080 | None | 1.000 | 8 | 0 | 2004 | 2019 | ||||||||
|
sclerostin | 0.474 | 0.808 | 0.87 |
|
phenotype | 0.070 | None | 0.857 | 7 | 0 | 2017 | 2019 | ||||||||
|
fibroblast growth factor 21 | 0.485 | 0.769 | 2.9E-02 |
|
phenotype | 0.060 | None | 1.000 | 6 | 0 | 2017 | 2019 | ||||||||
|
msh homeobox 2 | 0.539 | 0.769 | 0.26 |
|
phenotype | 0.060 | None | 1.000 | 6 | 0 | 2006 | 2019 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
phenotype | 0.050 | None | 1.000 | 5 | 0 | 2012 | 2019 | ||||||||
|
calcium sensing receptor | 0.410 | 0.846 | 4.7E-02 |
|
phenotype | 0.050 | None | 1.000 | 5 | 0 | 2015 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
phenotype | 0.050 | None | 1.000 | 5 | 0 | 2009 | 2019 | ||||||||
|
microRNA 223 | 0.433 | 0.808 |
|
phenotype | 0.050 | None | 1.000 | 5 | 0 | 2012 | 2019 | |||||||||
|
elastin | 0.415 | 0.885 | 2.1E-14 |
|
phenotype | 0.050 | None | 1.000 | 5 | 0 | 2015 | 2017 | ||||||||
|
growth arrest specific 6 | 0.500 | 0.769 | 3.4E-02 |
|
phenotype | 0.050 | None | 1.000 | 5 | 0 | 2008 | 2013 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
phenotype | 0.050 | None | 1.000 | 5 | 0 | 2008 | 2018 |