| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
granulin precursor | 0.435 | 0.846 | 7.0E-02 |
|
disease | 0.170 | None | 1.000 | 7 | 0 | 2010 | 2018 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.170 | None | 1.000 | 7 | 0 | 2011 | 2019 | ||||||||
|
transmembrane protein 106B | 0.590 | 0.462 | 0.33 |
|
disease | 0.120 | None | 0.500 | 2 | 0 | 2016 | 2017 | ||||||||
|
C9orf72-SMCR8 complex subunit | 0.496 | 0.769 | 1.1E-06 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2012 | 2012 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.120 | None | 1.000 | 2 | 1 | 2012 | 2016 | ||||||||
|
glutamate ionotropic receptor delta type subunit 2 | 0.670 | 0.500 | 1.00 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
charged multivesicular body protein 2B | 0.543 | 0.731 | 4.6E-06 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
protein tyrosine phosphatase non-receptor type 23 | 0.743 | 0.308 | 3.1E-02 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
XPA, DNA damage recognition and repair factor | 0.520 | 0.846 | 7.9E-05 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.100 | None | 0.930 | 43 | 0 | 1998 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.050 | None | 1.000 | 5 | 4 | 2012 | 2019 | ||||||||
|
neurofilament light | 0.488 | 0.769 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2017 | 2019 | |||||||||
|
spectrin alpha, non-erythrocytic 1 | 0.601 | 0.615 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2012 | 2017 | ||||||||
|
laminin subunit gamma 2 | 0.389 | 0.923 | 2.9E-12 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 2016 | 2018 | ||||||||
|
clusterin | 0.426 | 0.885 | 7.8E-05 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2011 | 2017 | ||||||||
|
colony stimulating factor 2 | 0.330 | 0.962 | 0.83 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 2016 | 2018 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2011 | 2018 | ||||||||
|
huntingtin | 0.548 | 0.654 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1997 | 2017 | ||||||||
|
neurogranin | 0.608 | 0.615 | 0.48 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2016 | 2017 | ||||||||
|
TAR DNA binding protein | 0.493 | 0.808 | 0.99 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2014 | 2019 | ||||||||
|
prolyl 4-hydroxylase subunit beta | 0.488 | 0.808 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2017 | 2019 | ||||||||
|
CLN5 intracellular trafficking protein | 0.705 | 0.269 | 1.7E-08 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2004 | 2018 | ||||||||
|
FMRP translational regulator 1 | 0.473 | 0.769 | 0.65 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2002 | 2007 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2019 | ||||||||
|
interferon beta 1 | 0.421 | 0.846 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2011 | 2018 |