Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.210 Therapeutic RGD Myoinositol Attenuates the Cell Loss and Biochemical Changes Induced by Kainic Acid Status Epilepticus. 27642592

2016
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0853897
Disease: Diabetic Cardiomyopathies
Diabetic Cardiomyopathies 		0.200 Therapeutic RGD The Rho kinase inhibitor, fasudil, ameliorates diabetes-induced cardiac dysfunction by improving calcium clearance and actin remodeling. 27576917

2017
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.200 Therapeutic RGD Simvastatin Attenuates Neuropathic Pain by Inhibiting the RhoA/LIMK/Cofilin Pathway. 27216618

2016
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.200 Biomarker RGD Large-Scale, Ion-Current-Based Proteomic Investigation of the Rat Striatal Proteome in a Model of Short- and Long-Term Cocaine Withdrawal. 27018876

2016
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0042847
Disease: Vitamin B 12 Deficiency
Vitamin B 12 Deficiency 		0.200 Biomarker RGD Maternal micronutrient deficiency leads to alteration in the kidney proteome in rat pups. 25982389

2015
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction 		0.200 Biomarker RGD Involvement of Rho-Kinase/LIM Kinase/Cofilin Signaling Pathway in Corporal Fibrosis after Cavernous Nerve Injury in Male Rats. 25923835

2015
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction 		0.200 Therapeutic RGD Restoration of erectile function by suppression of corporal apoptosis, fibrosis and corporal veno-occlusive dysfunction with rho-kinase inhibitors in a rat model of cavernous nerve injury. 25444982

2015
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0848548
Disease: hypertensive nephropathy
hypertensive nephropathy 		0.200 Biomarker RGD Cofilin1 is involved in hypertension-induced renal damage via the regulation of NF-κB in renal tubular epithelial cells. 26450610

2015
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.200 Biomarker RGD Ezrin is down-regulated in diabetic kidney glomeruli and regulates actin reorganization and glucose uptake via GLUT1 in cultured podocytes. 24726496

2014
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.200 Biomarker RGD LIMK-dependent actin polymerization in primary sensory neurons promotes the development of inflammatory heat hyperalgesia in rats. 24962708

2014
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy 		0.200 Biomarker RGD Decrease of Both Cofilin and LIM Kinase Phosphorylation in the Skeletal Muscles of Immobilization-induced Atrophy Rats. 24711688

2014
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.200 Therapeutic RGD Membrane ERα attenuates myocardial fibrosis via RhoA/ROCK-mediated actin remodeling in ovariectomized female infarcted rats. 24292258

2014
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Therapeutic RGD Cyclosporine A protects podocytes via stabilization of cofilin-1 expression in the unphosphorylated state. 24737737

2014
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0029866
Disease: Other ureteric obstruction
Other ureteric obstruction 		0.200 Biomarker RGD Proteomic identification of early changes in the renal cytoskeleton in obstructive uropathy. 24761003

2014
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0037769
Disease: West Syndrome
West Syndrome 		0.200 Biomarker RGD Proteomic analysis on infantile spasm and prenatal stress. 24994451

2014