Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.540 Biomarker RGD Involvement of microglia in the ethanol-induced neuropathic pain-like state in the rat. 17284346

2007
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.240 ModifyingMutation RGD Identification, isolation, and characterization of daintain (allograft inflammatory factor 1), a macrophage polypeptide with effects on insulin secretion and abundantly present in the pancreas of prediabetic BB rats. 9391121

1997
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.220 Biomarker RGD Time dependent changes of striatal interneurons after focal cerebral ischemia in rats. 18301954

2008
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0030193
Disease: Pain
Pain 		0.220 Biomarker RGD Activation of dorsal horn microglia contributes to diabetes-induced tactile allodynia via extracellular signal-regulated protein kinase signaling. 18186080

2008
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.220 Biomarker RGD Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability. 17178407

2006
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy 		0.200 Biomarker RGD Developmental motor deficits induced by combined fetal exposure to lipopolysaccharide and early neonatal hypoxia/ischemia: a novel animal model for cerebral palsy in very premature infants. 19010395

2009
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0014072
Disease: Experimental Autoimmune Encephalomyelitis
Experimental Autoimmune Encephalomyelitis 		0.200 Biomarker RGD CD4 microglial expression correlates with spontaneous clinical improvement in the acute Lewis rat EAE model. 19246105

2009
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0751955
Disease: Brain Infarction
Brain Infarction 		0.200 Biomarker RGD Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke. 19053043

2009
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0752308
Disease: Hypoxia-Ischemia, Brain
Hypoxia-Ischemia, Brain 		0.200 Biomarker RGD Delayed P2X4R expression after hypoxia-ischemia is associated with microglia in the immature rat brain. 19447505

2009
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0021368
Disease: Inflammation
Inflammation 		0.200 Biomarker RGD Inflammation regulates functional integration of neurons born in adult brain. 19020040

2008
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0085084
Disease: Motor Neuron Disease
Motor Neuron Disease 		0.200 Biomarker RGD Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. 18931666

2008
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0751865
Disease: Alcohol-Induced Disorders, Nervous System
Alcohol-Induced Disorders, Nervous System 		0.200 Biomarker RGD Distinct cell proliferation events during abstinence after alcohol dependence: microglia proliferation precedes neurogenesis. 18585922

2008
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.200 Biomarker RGD Expression of allograft inflammatory factor-1 in kidneys: A novel molecular component of podocyte. 17035944

2006
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.200 Biomarker RGD Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats. 16500929

2006
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0270824
Disease: Visual seizure
Visual seizure 		0.200 Biomarker RGD P2X7 receptor immunoreactive profile confined to resting and activated microglia in the epileptic brain. 16635480

2006
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0025309
Disease: Meningoencephalitis
Meningoencephalitis 		0.200 Biomarker RGD Expression of allograft inflammatory factor-1 and haeme oxygenase-1 in brains of rats infected with the neurotropic Borna disease virus. 16150122

2005
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0027814
Disease: Neuritis, Autoimmune, Experimental
Neuritis, Autoimmune, Experimental 		0.200 Biomarker RGD Experimental autoimmune neuritis induces differential microglia activation in the rat spinal cord. 15710454

2005