Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 239
Gene Symbol: ALOX12
ALOX12
CUI: C0028754
Disease: Obesity
Obesity 		0.220 Biomarker RGD We analyzed the expression of LO and proinflammatory cytokines in adipose tissue and adipocytes in obese Zucker rats, a widely studied genetic model of obesity, insulin resistance, and the metabolic syndrome. mRNA expression of 12-LO, 5-LO, and 5-LO-activating protein (FLAP) was upregulated in adipocytes and adipose tissue from obese Zucker rats compared with those from lean rats. 20978234

2011
Entrez Id: 239
Gene Symbol: ALOX12
ALOX12
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.210 Biomarker RGD An aldosterone-related system in the ventrolateral medulla oblongata of spontaneously hypertensive and Wistar-Kyoto rats. 16445702

2006
Entrez Id: 239
Gene Symbol: ALOX12
ALOX12
CUI: C0018801
Disease: Heart failure
Heart failure 		0.200 Biomarker RGD Genetic expression profiles during physiological and pathological cardiac hypertrophy and heart failure in rats. 15623566

2005
Entrez Id: 239
Gene Symbol: ALOX12
ALOX12
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.200 Biomarker RGD Genetic expression profiles during physiological and pathological cardiac hypertrophy and heart failure in rats. 15623566

2005
Entrez Id: 239
Gene Symbol: ALOX12
ALOX12
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.200 Biomarker RGD The expression of cyclooxygenases and lipoxygenases in renal ischemia-reperfusion injury. 15518705

2004