|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
0.700 |
SusceptibilityMutation |
ORPHANET |
Our data suggest an association between MHC class I and class II (HLA-A*29, HLA-B*51, HLA-DRB1*15, and HLA-DQB1*06) and susceptibility to SLE in the Saudi population.
|
23793423 |
2014 |
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
0.700 |
SusceptibilityMutation |
ORPHANET |
HLA-DRB1*13 was associated with AVE. All measured specificities of aPL-cardiolipin IgG and IgM, β2-glycoprotein-1 IgG, prothrombin (PT) IgG and a positive lupus anticoagulant test were associated with HLA-DRB1*04-while HLA-DRB1*13 was associated with IgG antibodies (β2-glycoprotein-1, cardiolipin and PT).
|
22893315 |
2013 |
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
0.700 |
SusceptibilityMutation |
ORPHANET |
Advances in lupus genetics.
|
23917156 |
2013 |
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
0.700 |
SusceptibilityMutation |
ORPHANET |
An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
|
23407388 |
2013 |
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
0.700 |
SusceptibilityMutation |
ORPHANET |
Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing.
|
22654485 |
2012 |
|
HLA-DRB1
|
Sarcoidosis
|
0.700 |
SusceptibilityMutation |
ORPHANET |
Genetic characterization and susceptibility for sarcoidosis in Japanese patients: risk factors of BTNL2 gene polymorphisms and HLA class II alleles.
|
22991420 |
2012 |
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
0.700 |
SusceptibilityMutation |
ORPHANET |
The most strongly associated SNP with SLE was the rs9271366 (odds ratio, OR = 1.70, p = 5.6 × 10(-5)) near the HLA-DRB1 gene.
|
21695597 |
2011 |
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
0.700 |
SusceptibilityMutation |
ORPHANET |
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
|
19838195 |
2009 |
|
HLA-DRB1
|
Narcolepsy
|
0.700 |
SusceptibilityMutation |
ORPHANET |
Comparison of clinical characteristics among narcolepsy with and without cataplexy and idiopathic hypersomnia without long sleep time, focusing on HLA-DRB1( *)1501/DQB1( *)0602 finding.
|
19410508 |
2009 |
|
HLA-DRB1
|
Narcolepsy
|
0.700 |
SusceptibilityMutation |
ORPHANET |
The susceptibility alleles found in Mexicans with narcolepsy are also present in Japanese and Caucasians; DRB1*04 linked protection has also been shown in Koreans.
|
18706091 |
2008 |
|
HLA-DRB1
|
Narcolepsy-Cataplexy Syndrome
|
0.530 |
SusceptibilityMutation |
ORPHANET |
Comparison of clinical characteristics among narcolepsy with and without cataplexy and idiopathic hypersomnia without long sleep time, focusing on HLA-DRB1( *)1501/DQB1( *)0602 finding.
|
19410508 |
2009 |
|
HLA-DRB1
|
Narcolepsy-Cataplexy Syndrome
|
0.530 |
SusceptibilityMutation |
ORPHANET |
The purpose of the present study was to investigate the association of HLA class II DRB1/DQB1 alleles with narcolepsy-cataplexy in Mexican Mestizo patients.
|
18706091 |
2008 |
|
HLA-DRB1
|
Lymphoma, Follicular
|
0.470 |
SusceptibilityMutation |
ORPHANET |
Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk.
|
23791106 |
2013 |
|
HLA-DRB1
|
Bullous pemphigoid
|
0.340 |
GeneticVariation |
ORPHANET |
Bullous pemphigoid: etiology, pathogenesis, and inducing factors: facts and controversies.
|
23806156 |
2013 |
|
HLA-DRB1
|
Bullous pemphigoid
|
0.340 |
GeneticVariation |
ORPHANET |
A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid.
|
8710911 |
1996 |
|
HLA-DRB1
|
Systemic onset juvenile chronic arthritis
|
0.320 |
SusceptibilityMutation |
ORPHANET |
Meta-analysis of imputed classic HLA-type associations in six study populations of Western European ancestry revealed that HLA-DRB1*11 and its defining amino acid residue, glutamate 58, were strongly associated with sJIA [P = 2.7 × 10(-16), OR 2.3 (1.9, 2.8)], as was the HLA-DRB1*11-HLA-DQA1*05-HLA-DQB1*03 haplotype [6.4 × 10(-17), OR 2.3 (1.9, 2.9)].
|
26598658 |
2015 |
|
HLA-DRB1
|
Diffuse Scleroderma
|
0.320 |
SusceptibilityMutation |
ORPHANET |
|
|
|
|
HLA-DRB1
|
CREST Syndrome
|
0.310 |
SusceptibilityMutation |
ORPHANET |
|
|
|
|
HLA-DRB1
|
Limbic encephalitis with leucine-rich glioma-inactivated 1 antibodies
|
0.300 |
SusceptibilityMutation |
ORPHANET |
Anti-LGI1 encephalitis is strongly associated with HLA-DR7 and HLA-DRB4.
|
28026046 |
2017 |
|
HLA-DRB1
|
Juvenile-Onset Still Disease
|
0.300 |
SusceptibilityMutation |
ORPHANET |
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.
|
26598658 |
2015 |
|
HLA-DRB1
|
Scleroderma, Limited
|
0.300 |
SusceptibilityMutation |
ORPHANET |
|
|
|