Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		1.000 Biomarker RGD HNF4alpha and HNF1alpha dysfunction as a molecular rational for cyclosporine induced posttransplantation diabetes mellitus. 19252740

2009
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C1852093
Disease: Maturity-Onset Diabetes of the Young, Type 1
Maturity-Onset Diabetes of the Young, Type 1 		1.000 Biomarker MGD

Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.300 Biomarker RGD Hepatocyte nuclear factor 4 alpha suppresses the development of hepatocellular carcinoma. 20876809

2010
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.300 Biomarker RGD Taken together, our results suggest that the inhibitory effect of HNF4α on HCC development might be attributed to suppression of hepatocyte EMT and cancer stem cell generation through an inhibition of β-catenin signaling pathways. 20876809

2010
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.280 Biomarker RGD Here, we report evidence of a suppressor role for HNF4α in liver cancer. 20876809

2010
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.230 Biomarker RGD We propose dysregulation of HNF 4 alpha and TRPC1 as a possible molecular rationale in diabetic nephropathy. 18184923

2008
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.210 Biomarker RGD Hepatocyte nuclear factor 4 alpha suppresses the development of hepatocellular carcinoma. 20876809

2010
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C2676033
Disease: Hepatoblastoma Caused By Somatic Mutation
Hepatoblastoma Caused By Somatic Mutation 		0.200 Biomarker RGD Hepatocyte nuclear factor 4 alpha suppresses the development of hepatocellular carcinoma. 20876809

2010
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C0015938
Disease: Fetal Macrosomia
Fetal Macrosomia 		0.200 Biomarker RGD Expression of CYP3A23/1, CYP3A2, PXR, CAR and HNF4alpha in large-for-gestational-age neonatal rats. 19435144

2009
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.200 Biomarker RGD HNF4 alpha and the Ca-channel TRPC1 are novel disease candidate genes in diabetic nephropathy. 18184923

2008