Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0270824
Disease: Visual seizure
Visual seizure 		0.500 Biomarker RGD Induction of DNA repair proteins, Ref-1 and XRCC1, in adult rat brain following kainic acid-induced seizures. 15854596

2005
Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.200 Biomarker RGD Melatonin preserves fetal growth in rats by protecting against ischemia/reperfusion-induced oxidative/nitrosative mitochondrial damage in the placenta. 18373555

2008
Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Spatial coordination of cell-adhesion molecules and redox cycling of iron in the microvascular inflammatory response to pulmonary injury. 17280489

2007
Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0027055
Disease: Myocardial Reperfusion Injury
Myocardial Reperfusion Injury 		0.200 Biomarker RGD Redox activation of Ref-1 potentiates cell survival following myocardial ischemia reperfusion injury. 17602955

2007
Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C2937358
Disease: Cerebral Hemorrhage
Cerebral Hemorrhage 		0.200 Biomarker RGD Deferoxamine-induced attenuation of brain edema and neurological deficits in a rat model of intracerebral hemorrhage. 15344903

2003
Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.200 Biomarker RGD Immunohistochemical study of p53-associated proteins in rat brain following lithium-pilocarpine status epilepticus. 11852039

2002
Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.200 Biomarker RGD Loss of Ref-1 protein expression precedes DNA fragmentation in apoptotic neurons. 9030714

1997