Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.400 Therapeutic CTD_human Resistance to cisplatin-induced apoptosis via PI3K-dependent survivin expression in a rat hepatoma cell line. 20514400

2010
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.400 Biomarker CTD_human Resistance to cisplatin-induced apoptosis via PI3K-dependent survivin expression in a rat hepatoma cell line. 20514400

2010
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker CTD_human Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation. 16818634

2006
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker CTD_human Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells. 16322251

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.400 Biomarker CTD_human [Effect of inhibiting survivin expression with antisense oligodeoxynucleotides on sensitivity of hepatocellular carcinoma cell lines HepG2 and HepG2/ADM to adriamycin]. 16086872

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.400 Therapeutic CTD_human [Effect of inhibiting survivin expression with antisense oligodeoxynucleotides on sensitivity of hepatocellular carcinoma cell lines HepG2 and HepG2/ADM to adriamycin]. 16086872

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.390 Biomarker CTD_human PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling. 26432044

2015
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.390 Biomarker CTD_human Overexpression of thymosin beta-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively. 16364925

2006
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.390 Biomarker CTD_human Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin. 16108013

2006
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.390 Therapeutic CTD_human Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin. 16108013

2006
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.390 Biomarker CTD_human Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation. 15981204

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.390 Therapeutic CTD_human Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation. 15981204

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Therapeutic CTD_human Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients. 18567002

2008
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker CTD_human Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients. 18567002

2008
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.370 Biomarker CTD_human Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation. 16818634

2006
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.370 Biomarker CTD_human Rebamipide inhibits gastric cancer growth by targeting survivin and Aurora-B. 15993841

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.370 Biomarker CTD_human Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells. 16322251

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Therapeutic CTD_human [Influence of short hairpin RNA on survivin mRNA expression and chemosensitivity to paclitaxel in ovarian cancer cells]. 16202317

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker CTD_human Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death. 16211241

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Therapeutic CTD_human Changes in survivin messenger RNA level during chemotherapy treatment in ovarian cancer cells. 15970709

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Therapeutic CTD_human Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death. 16211241

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker CTD_human [Influence of short hairpin RNA on survivin mRNA expression and chemosensitivity to paclitaxel in ovarian cancer cells]. 16202317

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.370 Biomarker CTD_human Changes in survivin messenger RNA level during chemotherapy treatment in ovarian cancer cells. 15970709

2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.360 Biomarker CTD_human PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling. 26432044

2015
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.360 Biomarker CTD_human Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation. 16818634

2006