Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.400 Biomarker CTD_human Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. 20099276

2010
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.400 Biomarker CTD_human Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. 20099276

2010
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.400 Biomarker CTD_human MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. 19487542

2009
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.350 Biomarker CTD_human Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. 20099276

2010
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.340 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0086543
Disease: Cataract
Cataract 		0.300 Biomarker CTD_human miR-221 promotes lens epithelial cells apoptosis through interacting with SIRT1 and E2F3. 30926320

2019
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0524524
Disease: Pseudoaphakia
Pseudoaphakia 		0.300 Biomarker CTD_human miR-221 promotes lens epithelial cells apoptosis through interacting with SIRT1 and E2F3. 30926320

2019
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C1510497
Disease: Lens Opacities
Lens Opacities 		0.300 Biomarker CTD_human Results showed that high expression of miR-221 was exhibited in ARC tissues compared with that in normal samples and associated with Lens Opacities Classification System III grades. 30926320

2019
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0019193
Disease: Hepatitis, Toxic
Hepatitis, Toxic 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C1262760
Disease: Hepatitis, Drug-Induced
Hepatitis, Drug-Induced 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0007621
Disease: Neoplastic Cell Transformation
Neoplastic Cell Transformation 		0.300 Biomarker CTD_human Aberrant expression of miR-638 contributes to benzo(a)pyrene-induced human cell transformation. 22048643

2012
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0019207
Disease: Hepatoma, Morris
Hepatoma, Morris 		0.300 Biomarker CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526

2011
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0019208
Disease: Hepatoma, Novikoff
Hepatoma, Novikoff 		0.300 Biomarker CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526

2011
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0023904
Disease: Liver Neoplasms, Experimental
Liver Neoplasms, Experimental 		0.300 Biomarker CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526

2011
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C0086404
Disease: Experimental Hepatoma
Experimental Hepatoma 		0.300 Biomarker CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526

2011
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker CTD_human Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. 20099276

2010
Entrez Id: 407006
Gene Symbol: MIR221
MIR221
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker CTD_human Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. 20099276

2010