Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C3151107
Disease: RETINITIS PIGMENTOSA 40 (disorder)
RETINITIS PIGMENTOSA 40 (disorder) 		0.900 Biomarker MGD Therapeutic margins in a novel preclinical model of retinitis pigmentosa. 23946405

2013
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C1876182
Disease: NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2
NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2 		0.900 Biomarker MGD Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene. 17267005

2007
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C1876182
Disease: NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2
NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2 		0.900 Biomarker MGD Genotype-phenotype correlation of mouse pde6b mutations. 16123450

2005
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C3151107
Disease: RETINITIS PIGMENTOSA 40 (disorder)
RETINITIS PIGMENTOSA 40 (disorder) 		0.900 Biomarker MGD Genotype-phenotype correlation of mouse pde6b mutations. 16123450

2005
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C1876182
Disease: NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2
NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2 		0.900 Biomarker MGD Reduced pupillary light responses in mice lacking cryptochromes. 12522242

2003
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C1876182
Disease: NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2
NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2 		0.900 Biomarker MGD Novel ENU-induced eye mutations in the mouse: models for human eye disease. 11929848

2002
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C3151107
Disease: RETINITIS PIGMENTOSA 40 (disorder)
RETINITIS PIGMENTOSA 40 (disorder) 		0.900 Biomarker MGD Novel ENU-induced eye mutations in the mouse: models for human eye disease. 11929848

2002
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C3151107
Disease: RETINITIS PIGMENTOSA 40 (disorder)
RETINITIS PIGMENTOSA 40 (disorder) 		0.900 Biomarker MGD Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice. 11114194

2000
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C1876182
Disease: NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2
NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2 		0.900 Biomarker MGD The Inheritance of a Retinal Abnormality in White Mice. 16576828

1924
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C0035334
Disease: Retinitis Pigmentosa
Retinitis Pigmentosa 		0.900 Biomarker MGD

Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C0154860
Disease: Hereditary retinal dystrophy
Hereditary retinal dystrophy 		0.200 Biomarker MGD Therapeutic margins in a novel preclinical model of retinitis pigmentosa. 23946405

2013
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C0154860
Disease: Hereditary retinal dystrophy
Hereditary retinal dystrophy 		0.200 Biomarker MGD Genotype-phenotype correlation of mouse pde6b mutations. 16123450

2005
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C0154860
Disease: Hereditary retinal dystrophy
Hereditary retinal dystrophy 		0.200 Biomarker MGD Novel ENU-induced eye mutations in the mouse: models for human eye disease. 11929848

2002
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C0154860
Disease: Hereditary retinal dystrophy
Hereditary retinal dystrophy 		0.200 Biomarker MGD Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice. 11114194

2000
Entrez Id: 5158
Gene Symbol: PDE6B
PDE6B
CUI: C0220701
Disease: RETINITIS PIGMENTOSA 1
RETINITIS PIGMENTOSA 1 		0.200 Biomarker MGD