Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0004096
Disease: Asthma
Asthma 		0.300 Biomarker RGD Genetic influences on asthma susceptibility in the developing lung. 20118217

2010
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0030305
Disease: Pancreatitis
Pancreatitis 		0.240 Biomarker RGD 5 Endogenous protease inhibitors (alpha(1)-antitrypsin, alpha(2)-macroglobulin) were low in normal tissues, but increased 45- and four-fold, respectively, during pancreatitis. 12770935

2003
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.220 Biomarker RGD Hepatic steatosis depresses alpha-1-antitrypsin levels in human and rat acute pancreatitis. 26634430

2015
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0157946
Disease: Osteoarthrosis, localized, not specified whether primary or secondary
Osteoarthrosis, localized, not specified whether primary or secondary 		0.200 Biomarker RGD Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilage. 20434574

2010
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0010481
Disease: Cushing Syndrome
Cushing Syndrome 		0.200 Biomarker RGD Loss of bone minerals and strength in rats with aldosteronism. 15475529

2004
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0020428
Disease: Hyperaldosteronism
Hyperaldosteronism 		0.200 Biomarker RGD Loss of bone minerals and strength in rats with aldosteronism. 15475529

2004
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0033687
Disease: Proteinuria
Proteinuria 		0.200 Biomarker RGD Acute-phase proteins before cerebral ischemia in stroke-prone rats: identification by proteomics. 11239198

2001
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.200 Biomarker RGD Role of alpha1-antitrypsin and detoxification functions of the liver in the pathogenesis of endotoxin-induced fever. 11140575

2000
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0023904
Disease: Liver Neoplasms, Experimental
Liver Neoplasms, Experimental 		0.200 Biomarker RGD Hepatic expression of acute-phase protein genes during carcinogenesis induced by peroxisome proliferators. 10569800

1999
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.200 Biomarker RGD Chronic hypoxic pulmonary hypertension in rats and increased elastolytic activity. 1836309

1991