Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.570 Biomarker RGD Kinin B1 and B2 receptor mRNA expression in the hypothalamus of spontaneously hypertensive rats. 12025958

2002
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.570 Biomarker RGD Pharmacologic and autoradiographic evidence for an up-regulation of kinin B(2) receptors in the spinal cord of spontaneously hypertensive rats. 11934804

2002
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0021368
Disease: Inflammation
Inflammation 		0.510 Biomarker RGD Effects of the bradykinin B2 receptor antagonist S 16118 (p-guanidobenzoyl-[Hyp3,Thi5,D-Tic7,Oic8]bradykinin) in different in vivo animal models of inflammation. 7791078

1995
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.500 Biomarker RGD Bradykinin receptors antagonists and nitric oxide synthase inhibitors in vincristine and streptozotocin induced hyperalgesia in chemotherapy and diabetic neuropathy rat model. 19300402

2009
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.500 Biomarker RGD Bradykinin B1 and B2 receptors, tumour necrosis factor alpha and inflammatory hyperalgesia. 10188975

1999
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy 		0.220 Biomarker RGD Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. 12489796

2002
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.210 Biomarker RGD Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. 12489796

2002
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0017638
Disease: Glioma
Glioma 		0.200 Biomarker RGD Selective tumor blood-brain barrier opening with the kinin B2 receptor agonist [Phe(8)psi(CH(2)NH)Arg(9)]-BK in a F98 glioma rat model: an MRI study. 20080302

2010
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.200 Biomarker RGD Selective tumor blood-brain barrier opening with the kinin B2 receptor agonist [Phe(8)psi(CH(2)NH)Arg(9)]-BK in a F98 glioma rat model: an MRI study. 20080302

2010
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0020541
Disease: Portal Hypertension
Portal Hypertension 		0.200 Biomarker RGD Splanchnic hyposensitivity to glypressin in a hemorrhage-transfused common bile duct-ligated rat model of portal hypertension: role of nitric oxide and bradykinin. 19950773

2009
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.200 Biomarker RGD Retinal plasma extravasation in streptozotocin-diabetic rats mediated by kinin B(1) and B(2) receptors. 18311190

2008
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy 		0.200 Biomarker RGD Role of kinin B1 and B2 receptors in a rat model of neuropathic pain. 18182225

2008
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.200 Biomarker RGD Autoradiographic distribution and alterations of kinin B(2) receptors in the brain and spinal cord of streptozotocin-diabetic rats. 16138314

2005
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.200 Biomarker RGD Treatment of severe pulmonary hypertension: a bradykinin receptor 2 agonist B9972 causes reduction of pulmonary artery pressure and right ventricular hypertrophy. 15878794

2005
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0004096
Disease: Asthma
Asthma 		0.200 Biomarker RGD Airway hyperresponsiveness to bradykinin induced by allergen challenge in actively sensitised Brown Norway rats. 14727005

2004
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.200 Biomarker RGD Autoradiographic analysis of rat brain kinin B1 and B2 receptors: normal distribution and alterations induced by epilepsy. 12746865

2003
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.200 Biomarker RGD Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. 12489796

2002
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Cyclooxygenase inhibitors attenuate bradykinin-induced vasoconstriction in septic isolated rat lungs. 10702448

2000
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0029799
Disease: Other specified forms of pleural effusion, except tuberculous
Other specified forms of pleural effusion, except tuberculous 		0.200 Biomarker RGD Effects of an orally active non-peptide bradykinin B2 receptor antagonist, FR173657, on plasma exudation in rat carrageenin-induced pleurisy. 9208140

1997
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0030305
Disease: Pancreatitis
Pancreatitis 		0.200 Biomarker RGD Effects of the bradykinin B2 receptor antagonist S 16118 (p-guanidobenzoyl-[Hyp3,Thi5,D-Tic7,Oic8]bradykinin) in different in vivo animal models of inflammation. 7791078

1995