Source: ORPHANET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C1838457
Disease: FANCONI ANEMIA, COMPLEMENTATION GROUP D1
FANCONI ANEMIA, COMPLEMENTATION GROUP D1 		0.920 GermlineCausalMutation ORPHANET Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2. 16825431

2007
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C1838457
Disease: FANCONI ANEMIA, COMPLEMENTATION GROUP D1
FANCONI ANEMIA, COMPLEMENTATION GROUP D1 		0.920 GermlineCausalMutation ORPHANET Biallelic BRCA2 mutations are associated with multiple malignancies in childhood including familial Wilms tumour. 15689453

2005
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C1838457
Disease: FANCONI ANEMIA, COMPLEMENTATION GROUP D1
FANCONI ANEMIA, COMPLEMENTATION GROUP D1 		0.920 GermlineCausalMutation ORPHANET Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood. 14670928

2004
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0677776
Disease: Hereditary Breast and Ovarian Cancer Syndrome
Hereditary Breast and Ovarian Cancer Syndrome 		0.800 GermlineCausalMutation ORPHANET Hereditary ovarian cancer. 16112002

2005
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.720 GeneticVariation ORPHANET Biallelic BRCA2 mutations are associated with multiple malignancies in childhood including familial Wilms tumour. 15689453

2005
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C2931038
Disease: Pancreatic carcinoma, familial
Pancreatic carcinoma, familial 		0.400 SusceptibilityMutation ORPHANET To study these relationships in more detail, we examined whether BRCA2 germline mutations are associated with familial pancreatic cancer. 12569143

2003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.400 SusceptibilityMutation ORPHANET BRCA1 and BRCA2 mutation analysis of early-onset and familial breast cancer cases in Mexico. 12442275

2002
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.400 SusceptibilityMutation ORPHANET Molecular characterization of germline mutations in the BRCA1 and BRCA2 genes from breast cancer families in Taiwan. 10323242

1999
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.400 SusceptibilityMutation ORPHANET High proportion of missense mutations of the BRCA1 and BRCA2 genes in Japanese breast cancer families. 9609997

1998
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		0.380 SusceptibilityMutation ORPHANET Rare germline mutations in the BRCA2 gene are associated with early-onset prostate cancer. 17700570

2007
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C4749652
Disease: Hereditary site-specific ovarian cancer syndrome
Hereditary site-specific ovarian cancer syndrome 		0.300 SusceptibilityMutation ORPHANET Hereditary ovarian cancer. 16112002

2005