×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Rheumatoid arthritis patients showed high TNFalpha mRNA expression (1.33-fold).18797411 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
BAT1 promoter polymorphism is associated with rheumatoid arthritis susceptibility.
18381799 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
Potential novel biomarkers of disease activity in rheumatoid arthritis patients: CXCL13, CCL23, transforming growth factor alpha, tumor necrosis factor receptor superfamily member 9, and macrophage colony-stimulating factor.
18668547 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures.
19017992 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Polymorphism in the tumor necrosis factor-alpha gene promoter is associated with severity of rheumatoid arthritis in the Czech population.
17562093 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Rheumatoid arthritis, periodontal disease and coronary artery disease.
17763921 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Tumour necrosis factor (TNF)alpha -308 G/G promoter polymorphism and TNFalpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis.
17343250 2007
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
TNF microsatellites polymorphism is associated with rheumatoid arthritis. Confirming evidence in northwestern Colombians.
17631742 2007
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
Increased nuclear factor-kappaB activation in peripheral blood monocytes of patients with rheumatoid arthritis is mediated primarily by tumor necrosis factor-alpha.
17896809 2007
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution?
16446172 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
Expression of TNF-alpha, tristetraprolin, T-cell intracellular antigen-1 and Hu antigen R genes in synovium of patients with rheumatoid arthritis.
16820934 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
JAB1 determines the response of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor-alpha.
16936264 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression.
16564576 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death.
16751383 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Immune complexes from rheumatoid arthritis synovial fluid induce FcgammaRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor-alpha by peripheral blood mononuclear cells.
16569263 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Tumor necrosis factor-alpha -308 promoter polymorphism contributes independently to HLA alleles in the severity of rheumatoid arthritis in Mexicans.
15725578 2005
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Overlapping gene expression profiles in rheumatoid fibroblast-like synoviocytes induced by the proinflammatory cytokines interleukin-1 beta and tumor necrosis factor.
15723199 2005
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
[Role of TNF-alpha and cytokines in the physiopathology of rheumatoid arthritis. Therapeutic perspectives].
14979058 2003
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
The effect of HLA-DR on susceptibility to rheumatoid arthritis is influenced by the associated lymphotoxin alpha-tumor necrosis factor haplotype.
12528108 2003
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Susceptibility for and clinical manifestations of rheumatoid arthritis are associated with polymorphisms of the TNF-alpha, IL-1beta, and IL-1Ra genes.
11838837 2002
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Anemia of chronic disease in rheumatoid arthritis is associated with increased apoptosis of bone marrow erythroid cells: improvement following anti-tumor necrosis factor-alpha antibody therapy.
12091338 2002
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
Regulation of TNF-alpha-mediated hyperplasia through TNF receptors, TRAFs, and NF-kappaB in synoviocytes obtained from patients with rheumatoid arthritis.
12067756 2002
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Bone marrow progenitor cell reserve and function and stromal cell function are defective in rheumatoid arthritis: evidence for a tumor necrosis factor alpha-mediated effect.
11861275 2002
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
Anti-TNF therapy for rheumatoid arthritis and other inflammatory diseases.
11725485 2001
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Ulcerative Colitis
0.600
Biomarker
LHGDN
Because UC patients are at increased risk for developing colorectal cancer (CRC), we investigated if there was an association between SNPs in the promoter of the TNF-alpha gene and UC -CRC.
18289203 2008