Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.350 Biomarker LHGDN Expression of orotate phosphoribosyltransferase in colorectal carcinoma: an immunohistochemical analysis in several components of neoplastic lesions. 18949394

2008

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.350 AlteredExpression LHGDN Clinical implications of thymidylate synthetase, dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activity levels in colorectal carcinoma following radical resection and administration of adjuvant 5-FU chemotherapy. 18597678

2008

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.350 Biomarker LHGDN Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer. 14562021

2003

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.320 AlteredExpression LHGDN Overexpression of orotate phosphoribosyl transferase in hormone-refractory prostate cancer. 19082440

2009

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.320 AlteredExpression LHGDN Decreased orotate phosphoribosyltransferase activity produces 5-fluorouracil resistance in a human gastric cancer cell line. 19020740

2008

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.320 AlteredExpression LHGDN Expression of thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, and orotate phosphoribosyl transferase in prostate cancer. 15999119

2005

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.320 Biomarker LHGDN Impact of orotate phosphoribosyl transferase activity as a predictor of lymph node metastasis in gastric cancer. 16142362

2005

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.310 Biomarker LHGDN Our data suggest that OPRT is involved in early events of pancreatic and gallbladder carcinogenesis and invasion of HCC. 17607371

2007

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker LHGDN Our results suggest that OPRT is involved in the invasion and metastasis of CRC. 18949394

2008

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker LHGDN Impact of orotate phosphoribosyl transferase activity as a predictor of lymph node metastasis in gastric cancer. 16142362

2005

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
0.010 AlteredExpression LHGDN Expression of orotate phosphoribosyl transferase in human pancreatic cancer: implication for the efficacy of uracil and tegafur-based adjuvant chemotherapy. 17549346

2007

Entrez Id: 7372
Gene Symbol: UMPS
UMPS
CUI: C2937421
Disease: Prostatic Hyperplasia
Prostatic Hyperplasia
0.010 AlteredExpression LHGDN Expression of thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, and orotate phosphoribosyl transferase in prostate cancer. 15999119

2005