| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
serine/threonine kinase 11 | 0.435 | 0.808 | 0.99 |
|
disease | 1.000 | definitive | 0.992 | 258 | 77 | 1997 | 2019 | ||||||||
|
defensin alpha 5 | 0.695 | 0.423 | 5.2E-06 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2008 | 2008 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.080 | None | 1.000 | 8 | 1 | 2000 | 2018 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 1998 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2000 | 2019 | ||||||||
|
cytochrome P450 family 19 subfamily A member 1 | 0.410 | 0.885 | 1.7E-05 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2001 | 2018 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2002 | 2004 | ||||||||
|
cytochrome c oxidase subunit II | 0.352 | 0.962 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2003 | 2003 | |||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1999 | 2015 | ||||||||
|
H3 histone pseudogene 10 | 0.350 | 0.846 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1999 | 2015 | |||||||||
|
MT-CO2 pseudogene 12 | 0.368 | 0.962 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2003 | 2003 | |||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2013 | 2014 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2001 | ||||||||
|
menin 1 | 0.444 | 0.808 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2002 | ||||||||
|
TSC complex subunit 2 | 0.439 | 0.808 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2004 | 2005 | ||||||||
|
PTPRF interacting protein alpha 1 | 0.760 | 0.269 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2002 | ||||||||
|
myosin heavy chain 11 | 0.528 | 0.731 | 0.77 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2008 | 2008 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 1999 | 2013 | ||||||||
|
protein kinase cAMP-dependent type I regulatory subunit alpha | 0.401 | 0.846 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2010 | 2011 | ||||||||
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.450 | 0.885 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2005 | ||||||||
|
centromere protein J | 0.546 | 0.846 | 2.1E-27 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2002 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2019 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2005 | 2010 | ||||||||
|
serine/threonine kinase 11 interacting protein | 0.861 | 0.192 | 8.6E-20 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2002 | ||||||||
|
cytochrome P450 family 2 subfamily B member 6 | 0.428 | 0.846 | 1.9E-10 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 1993 | 1994 |