Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 0.971 103 3 1999 2020
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 46 0 2001 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 0.977 44 1 2001 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.380 0.846 0.46
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 40 0 1998 2020
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 29 0 2010 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 28 0 2002 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 0.964 28 0 2004 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 0.962 26 0 1994 2020
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1
vascular cell adhesion molecule 1 0.422 0.808 0.80
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 26 1 2010 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 25 0 1995 2019
Entrez Id: 7450
Gene Symbol: VWF
VWF
von Willebrand factor 0.408 0.885 3.2E-25
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 22 1 2003 2019
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
2,4-dienoyl-CoA reductase 1 0.426 0.885 4.5E-14
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 21 0 2001 2020
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
adiponectin, C1Q and collagen domain containing 0.376 0.885 4.6E-09
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 20 0 2003 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 19 0 2000 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 18 0 2001 2019
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.370 0.923 2.4E-07
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 18 0 2001 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 17 0 2010 2019
Entrez Id: 4973
Gene Symbol: OLR1
OLR1
oxidized low density lipoprotein receptor 1 0.544 0.769 7.2E-03
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 17 1 2002 2019
Entrez Id: 6401
Gene Symbol: SELE
SELE
selectin E 0.447 0.808 7.9E-10
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 17 0 2005 2019
Entrez Id: 5806
Gene Symbol: PTX3
PTX3
pentraxin 3 0.457 0.808 7.0E-05
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 14 0 2013 2019
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
angiopoietin 2 0.410 0.846 0.83
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 14 0 2001 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 14 0 2011 2020
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 11 0 2007 2019
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
cytochrome b-245 beta chain 0.452 0.885 1.00
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 11 0 2012 2020
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
ROS proto-oncogene 1, receptor tyrosine kinase 0.439 0.885 1.6E-72
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction
phenotype 0.100 None 1.000 11 0 2017 2020