| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.100 | None | 0.942 | 52 | 0 | 1992 | 2019 | ||||||||
|
RNA binding motif protein 45 | 0.383 | 0.846 | 2.1E-10 |
|
disease | 0.100 | None | 0.970 | 33 | 0 | 1992 | 2019 | ||||||||
|
cytochrome P450 family 2 subfamily D member 6 | 0.437 | 0.885 | 1.1E-25 |
|
disease | 0.100 | None | 1.000 | 19 | 0 | 1989 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.818 | 11 | 1 | 1999 | 2019 | ||||||||
|
cytotoxic T-lymphocyte associated protein 4 | 0.369 | 0.923 | 0.94 |
|
disease | 0.090 | None | 0.889 | 9 | 1 | 2000 | 2015 | ||||||||
|
glutamic--pyruvic transaminase | 0.403 | 0.923 | 3.6E-19 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2001 | 2019 | ||||||||
|
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase | 0.656 | 0.423 | 1.6E-08 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2000 | 2020 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.070 | None | 1.000 | 7 | 2 | 1999 | 2019 | ||||||||
|
amelogenin X-linked | 0.599 | 0.769 | 7.5E-02 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2001 | 2019 | ||||||||
|
interleukin 2 receptor subunit alpha | 0.389 | 0.885 | 5.5E-02 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2005 | 2019 | ||||||||
|
Cholangitis, primary sclerosing | 0.603 | 0.731 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2010 | 2019 | |||||||||
|
interferon stimulated exonuclease gene 20 | 0.414 | 0.846 | 2.9E-03 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2005 | 2019 | ||||||||
|
forkhead box P3 | 0.368 | 0.846 | 0.99 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2008 | 2019 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
disease | 0.050 | None | 0.800 | 5 | 0 | 2010 | 2019 | ||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2002 | 2019 | ||||||||
|
autoimmune regulator | 0.516 | 0.808 | 4.0E-12 |
|
disease | 0.050 | None | 0.800 | 5 | 1 | 2001 | 2009 | ||||||||
|
major histocompatibility complex, class II, DP beta 1 | 0.453 | 0.923 | 5.3E-10 |
|
disease | 0.050 | None | 1.000 | 5 | 1 | 1992 | 2018 | ||||||||
|
interleukin 4 | 0.332 | 0.962 | 4.7E-03 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2004 | 2018 | ||||||||
|
programmed cell death 1 | 0.402 | 0.846 | 0.42 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 2017 | 2020 | ||||||||
|
thiopurine S-methyltransferase | 0.593 | 0.692 | 7.1E-06 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2002 | 2019 | ||||||||
|
enamelin | 0.674 | 0.346 | 1.3E-12 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1999 | 2018 | ||||||||
|
interleukin 2 | 0.336 | 0.885 | 0.48 |
|
disease | 0.040 | None | 0.750 | 4 | 2 | 2008 | 2018 | ||||||||
|
actin beta | 0.325 | 0.923 | 0.99 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1999 | 2017 | ||||||||
|
formimidoyltransferase cyclodeaminase | 0.722 | 0.423 | 5.5E-15 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1999 | 2016 | ||||||||
|
major histocompatibility complex, class I, A | 0.370 | 0.846 | 1.3E-03 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1997 | 2019 |