Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD The elevation of circulating fibroblast growth factor 23 without kidney disease does not increase cardiovascular disease risk. 29735309

2018
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis. 22527485

2012
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD Mineralizing enthesopathy is a common feature of renal phosphate-wasting disorders attributed to FGF23 and is exacerbated by standard therapy in hyp mice. 23038738

2012
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD A novel Phex mutation in a new mouse model of hypophosphatemic rickets. 22573557

2012
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD A mouse model with postnatal endolymphatic hydrops and hearing loss. 18289812

2008
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD A novel Phex mutation with defective glycosylation causes hypophosphatemia and rickets in mice. 17710565

2008
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes. 15976027

2005
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia-related abnormalities in mice. 15029877

2004
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD Effect of gene dose and parental origin on bone histomorphometry in X-linked Hyp mice. 14751570

2004
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD An ethyl-nitrosourea-induced point mutation in phex causes exon skipping, x-linked hypophosphatemia, and rickets. 12414538

2002
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition. 11159866

2001
Entrez Id: 5251
Gene Symbol: PHEX
PHEX
CUI: C1845168
Disease: Hypophosphatemic Rickets, X-Linked Recessive
Hypophosphatemic Rickets, X-Linked Recessive 		0.500 Biomarker MGD Malabsorption of phosphate by the intestines of young X-linked hypophosphatemic mice. 3145795

1988