| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.100 | None | 1.000 | 22 | 0 | 1996 | 2011 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.100 | None | 0.941 | 17 | 1 | 1996 | 2017 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.100 | None | 1.000 | 15 | 0 | 1990 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 1995 | 2019 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.050 | None | 0.800 | 5 | 0 | 2005 | 2019 | ||||||||
|
androgen receptor | 0.351 | 0.846 | 0.99 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 1999 | 2018 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2011 | 2017 | ||||||||
|
progesterone receptor | 0.426 | 0.885 | 5.1E-02 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 2002 | 2019 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2004 | 2009 | ||||||||
|
cytochrome P450 family 19 subfamily A member 1 | 0.410 | 0.885 | 1.7E-05 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2005 | 2018 | ||||||||
|
catechol-O-methyltransferase | 0.400 | 0.923 | 1.1E-06 |
|
disease | 0.030 | None | 1.000 | 3 | 3 | 2004 | 2013 | ||||||||
|
kallikrein related peptidase 3 | 0.443 | 0.885 | 4.4E-06 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 1997 | 1998 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 1996 | 2013 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2009 | 2013 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2012 | ||||||||
|
prohibitin | 0.511 | 0.846 | 0.76 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2012 | 2013 | ||||||||
|
cytochrome P450 family 17 subfamily A member 1 | 0.462 | 0.769 | 2.6E-04 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2003 | 2005 | ||||||||
|
Ras association domain family member 1 | 0.420 | 0.808 | 4.9E-06 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2011 | 2012 | ||||||||
|
retinoic acid receptor responder 2 | 0.519 | 0.731 | 2.7E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
RAD51 paralog B | 0.556 | 0.769 | 2.1E-15 |
|
disease | 0.010 | None | 1.000 | 1 | 3 | 2016 | 2016 | ||||||||
|
mindbomb E3 ubiquitin protein ligase 1 | 0.438 | 0.769 | 3.4E-88 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2005 | 2005 | ||||||||
|
ATP binding cassette subfamily C member 11 | 0.565 | 0.769 | 4.0E-46 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2011 | 2011 | ||||||||
|
NLR family pyrin domain containing 2 | 0.515 | 0.731 | 1.4E-38 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
nuclear receptor subfamily 1 group I member 2 | 0.418 | 0.846 | 7.3E-09 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2007 | 2007 |