Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		superoxide dismutase 1 0.379 0.962 0.18
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.600 None 0.973 53 7 1994 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1 		paraoxonase 1 0.409 0.885 9.8E-11
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.350 None 0.600 5 0 2007 2012
Entrez Id: 1270
Gene Symbol: CNTF
CNTF 		ciliary neurotrophic factor 0.561 0.615 2.3E-05
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.310 None < 0.001 1 0 2002 2002
Entrez Id: 1639
Gene Symbol: DCTN1
DCTN1 		dynactin subunit 1 0.597 0.500 8.4E-02
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.310 None 1.000 1 0 2017 2017
Entrez Id: 3297
Gene Symbol: HSF1
HSF1 		heat shock transcription factor 1 0.507 0.769 0.75
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.310 None 1.000 1 0 2013 2016
Entrez Id: 1509
Gene Symbol: CTSD
CTSD 		cathepsin D 0.478 0.846 9.2E-04
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.310 None 1.000 1 0 2002 2019
Entrez Id: 1471
Gene Symbol: CST3
CST3 		cystatin C 0.436 0.808 3.9E-03
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.310 None 1.000 1 0 2002 2017
Entrez Id: 1191
Gene Symbol: CLU
CLU 		clusterin 0.426 0.885 7.8E-05
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.310 None 1.000 1 0 1999 2002
Entrez Id: 5630
Gene Symbol: PRPH
PRPH 		peripherin 0.623 0.462 4.8E-14
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.310 None 1.000 1 0 2011 2011
Entrez Id: 2326
Gene Symbol: FMO1
FMO1 		flavin containing dimethylaniline monoxygenase 1 0.805 0.269 9.1E-11
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.310 None 1.000 1 0 2006 2006
Entrez Id: 7124
Gene Symbol: TNF
TNF 		tumor necrosis factor 0.231 0.962 0.80
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.310 None 1.000 1 0 2002 2010
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.210 None 1.000 1 0 2001 2008
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		superoxide dismutase 2 0.379 0.923 0.15
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.210 None 1.000 1 0 1998 2005
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72 		C9orf72-SMCR8 complex subunit 0.496 0.769 1.1E-06
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.200 None 0.957 21 3 2012 2019
Entrez Id: 23025
Gene Symbol: UNC13A
UNC13A 		unc-13 homolog A 0.705 0.423 1.00
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.130 None 1.000 3 1 2009 2019
Entrez Id: 23261
Gene Symbol: CAMTA1
CAMTA1 		calmodulin binding transcription activator 1 0.599 0.615 1.00
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.110 None 1.000 1 0 2016 2016
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4 		erb-b2 receptor tyrosine kinase 4 0.455 0.846 1.00
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.110 None 1.000 1 0 2014 2017
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		TAR DNA binding protein 0.493 0.808 0.99
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.100 None 1.000 38 0 2007 2020
Entrez Id: 2521
Gene Symbol: FUS
FUS 		FUS RNA binding protein 0.470 0.846 1.00
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.100 None 1.000 16 0 2010 2017
Entrez Id: 3483
Gene Symbol: IGFALS
IGFALS 		insulin like growth factor binding protein acid labile subunit 0.511 0.846 5.4E-11
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.090 None 1.000 9 1 1997 2018
Entrez Id: 10133
Gene Symbol: OPTN
OPTN 		optineurin 0.548 0.808 5.9E-18
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.090 None 1.000 9 0 2011 2019
Entrez Id: 283
Gene Symbol: ANG
ANG 		angiogenin 0.511 0.769 0.29
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.070 None 1.000 7 0 2008 2019
Entrez Id: 7415
Gene Symbol: VCP
VCP 		valosin containing protein 0.469 0.923 1.00
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.070 None 1.000 7 0 2012 2015
Entrez Id: 348
Gene Symbol: APOE
APOE 		apolipoprotein E 0.338 0.962 1.9E-03
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.050 None 1.000 5 0 1995 2011
Entrez Id: 55277
Gene Symbol: FGGY
FGGY 		FGGY carbohydrate kinase domain containing 0.890 0.115 3.2E-18
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease 0.050 None 0.600 5 0 2010 2014