Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.400 Biomarker CTD_human Refinement of the prediction of N-acetyltransferase 2 (NAT2) phenotypes with respect to enzyme activity and urinary bladder cancer risk. 24221535

2013

Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.400 Biomarker CTD_human A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. 20972438

2010

Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.400 Biomarker CTD_human Assuming a very low prior probability of 0.000001, similar to a probability assumed for a randomly selected single-nucleotide polymorphism in a genome-wide association study, and statistical power to detect an OR of 1.5, 4 associations were considered noteworthy as denoted by an FPRP value <0.2: GSTM1 null and bladder cancer (OR, 1.5; 95% CI, 1.3-1.6; P = 1.9 x 10(-14)), NAT2 slow acetylator and bladder cancer (OR, 1.46; 95% CI, 1.26-1.68; P = 2.5 x 10(-7)), MTHFR C677T and gastric cancer (OR, 1.52; 95% CI, 1.31-1.77; P = 4.9 x 10(-8)), and GSTM1 null and acute leukemia (OR, 1.20; 95% CI, 1.14-1.25; P = 8.6 x 10(-15)). 18505952

2008

Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.400 Biomarker CTD_human Acetylation genotype and the genetic susceptibility to prostate cancer in a southern European population. 15717312

2005

Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.400 Biomarker CTD_human The NAT2* slow acetylator genotype is associated with bladder cancer in Taiwanese, but not in the Black Foot Disease endemic area population. 10022756

1998