Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker CTD_human Quercetin inhibits left ventricular hypertrophy in spontaneously hypertensive rats and inhibits angiotensin II-induced H9C2 cells hypertrophy by enhancing PPAR-γ expression and suppressing AP-1 activity. 24039778

2013
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Therapeutic CTD_human Quercetin inhibits left ventricular hypertrophy in spontaneously hypertensive rats and inhibits angiotensin II-induced H9C2 cells hypertrophy by enhancing PPAR-γ expression and suppressing AP-1 activity. 24039778

2013
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker CTD_human Common genetic variants at the NPPA-NPPB locus found to be associated with circulating natriuretic peptide concentrations contribute to interindividual variation in blood pressure and hypertension. 19219041

2009
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Therapeutic CTD_human Common genetic variants at the NPPA-NPPB locus found to be associated with circulating natriuretic peptide concentrations contribute to interindividual variation in blood pressure and hypertension. 19219041

2009
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker CTD_human Neutralization of proANP (1-30) exacerbates hypertension in the spontaneously hypertensive rat. 12940879

2003
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Therapeutic CTD_human Neutralization of proANP (1-30) exacerbates hypertension in the spontaneously hypertensive rat. 12940879

2003
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker CTD_human Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats. 9869009

1998
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Therapeutic CTD_human Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats. 9869009

1998
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker CTD_human Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension. 7839143

1995
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Therapeutic CTD_human Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension. 7839143

1995
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker CTD_human Central cardiovascular effects of AVP and ANP in normotensive and spontaneously hypertensive rats. 8188982

1994
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Therapeutic CTD_human Central cardiovascular effects of AVP and ANP in normotensive and spontaneously hypertensive rats. 8188982

1994
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Therapeutic CTD_human Severe proteinuria without impairment of sodium and volume excretion after puromycin aminonucleoside administration in rats. 2526952

1989
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker CTD_human Severe proteinuria without impairment of sodium and volume excretion after puromycin aminonucleoside administration in rats. 2526952

1989