DisGeNET - a database of gene-disease associations

Gene: SIRT1 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	23411
Gene Symbol:	SIRT1

SIRT1

CUI:	C0271650
Disease:	Impaired glucose tolerance

Impaired glucose tolerance

0.350

Therapeutic

CTD_human

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver.

2011