DisGeNET - a database of gene-disease associations

Gene: TNFSF10 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	8743
Gene Symbol:	TNFSF10

TNFSF10

CUI:	C0279702
Disease:	Conventional (Clear Cell) Renal Cell Carcinoma

Conventional (Clear Cell) Renal Cell Carcinoma

0.380

Therapeutic

CTD_human

The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP.

2010